亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
全免费午夜一级毛片**,国产精品一区二区AV日韩在线
Rabbit Anti-ARHGEF18/PE-Cy3 Conjugated antibody (bs-7144R-PE-Cy3)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-7144R-PE-Cy3
英文名稱 Rabbit Anti-ARHGEF18/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的G蛋白偶聯(lián)受體ARHGEF18抗體
別    名 p114RhoGEF; 114 kDa Rho specific guanine nucleotide exchange factor; ARHGEF 18; ARHGEF18; KIAA0521; MGC15913; p114 Rho GEF; p114-Rho-GEF; Rho specific guanine nucleotide exchange factor p114; Rho-specific guanine nucleotide exchange factor p114; Rho/Rac guanine nucleotide exchange factor (GEF) 18; Rho/Rac guanine nucleotide exchange factor 18; SA RhoGEF; Septin associated RhoGEF; ARHGI_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 131kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ARHGEF18/p114RhoGEF
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008].

Function:
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). p114RgoGEF cts as guanine nucleotide exchange factor (GEF) for RhoA GTPases. It may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It also act as a GEF for RAC1, inducing production of reactive oxygen species (ROS), but does not act as a GEF for CDC42. The G protein beta-gamma (Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production.

Subunit:
Interacts with SEPT9; interaction may inhibit GEF activity. Interacts with Gbetagamma subunits GNB1 and GNG2.

Subcellular Location:
Cytoplasm. Note: Colocalizes with actin stress fibers.

Tissue Specificity:
Expressed in all tissues tested with highest expression in kidney and pancreas. Weakly or not expressed in liver, skeletal muscle and testis.

Similarity:
Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain.

Database links:

Entrez Gene: 23370 Human

Entrez Gene: 102098 Mouse

Entrez Gene: 304193 Rat

SwissProt: Q6ZSZ5 Human

SwissProt: Q6P9R4 Mouse

Unigene: 465761 Human

Unigene: 736818 Human

Unigene: 170461 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
宝贝儿乖我们继续H | 中文字幕无线码免费人妻 | 性色A码一区二区三区天美传媒 | 91精品国产综合久久精品色欲 | 亚洲成a人v欧美综合天堂下载 | 亚洲国产精品嫩草影院永久 | 又爽又高潮的BB视频免费看 | 久久久久久久久久久免费精品国产 | 成年免费视频黄网站在线观看 | 中文字幕人妻紧无码专区 | 欧美日韩在线精品视频二区下载 | 日本阿v片在线播放免费 | 国产精品欧美久久久久天天影视 | 成人午夜国产内射主播 | 精品自拍视频五区六区在线观看 | 亚洲AV福利天堂一区二区三 | 国产黄A一级二级三级看三区 | 国产日韓无码一区二区三区久久区 | 人妻少妇被猛烈进入中文字幕 | 午夜尤物禁止18点击进入 | 日欧精品卡2卡3卡4卡5卡L | 精品欧美一区二区三区四区 | 97无码免费人妻超级碰碰夜夜 | 久久99精品久久久久久园产越南 | 国产无遮挡无码视频在线观看不卡 | 狠狠躁18三区二区一区 | 国产亚洲综合99久久系列 | 国产精品免费一级在线观看 | 国产-第1页-浮力影院 | 精品欧美一区二区三区久久久 | 国产精品小仙女思妍肉丝 | 久久99热狠狠色精品一区 | 日日噜噜夜夜爽爽 | 999在线视频精品免费播放观看 | 久久国产V一级毛多内射 | 国产精品高清视亚洲一区二区 | 在线日韩制服中文字幕视频 | 亚洲无人区码一码二码三码四码 | 国产96在线视频播放网站 | 日韩欧美精品在线观看 | A级国产乱理伦片在线观看 国产一区二区三区影院 |