亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日韩成人电影在线观看,一区二区乱子伦在线播放
Rabbit Anti-ARHGEF18/BF350 Conjugated antibody (bs-7144R-BF350)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-7144R-BF350
英文名稱 Rabbit Anti-ARHGEF18/BF350 Conjugated antibody
中文名稱 BF350標(biāo)記的G蛋白偶聯(lián)受體ARHGEF18抗體
別    名 p114RhoGEF; 114 kDa Rho specific guanine nucleotide exchange factor; ARHGEF 18; ARHGEF18; KIAA0521; MGC15913; p114 Rho GEF; p114-Rho-GEF; Rho specific guanine nucleotide exchange factor p114; Rho-specific guanine nucleotide exchange factor p114; Rho/Rac guanine nucleotide exchange factor (GEF) 18; Rho/Rac guanine nucleotide exchange factor 18; SA RhoGEF; Septin associated RhoGEF; ARHGI_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 131kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ARHGEF18/p114RhoGEF
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008].

Function:
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). p114RgoGEF cts as guanine nucleotide exchange factor (GEF) for RhoA GTPases. It may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It also act as a GEF for RAC1, inducing production of reactive oxygen species (ROS), but does not act as a GEF for CDC42. The G protein beta-gamma (Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production.

Subunit:
Interacts with SEPT9; interaction may inhibit GEF activity. Interacts with Gbetagamma subunits GNB1 and GNG2.

Subcellular Location:
Cytoplasm. Note: Colocalizes with actin stress fibers.

Tissue Specificity:
Expressed in all tissues tested with highest expression in kidney and pancreas. Weakly or not expressed in liver, skeletal muscle and testis.

Similarity:
Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain.

Database links:

Entrez Gene: 23370 Human

Entrez Gene: 102098 Mouse

Entrez Gene: 304193 Rat

SwissProt: Q6ZSZ5 Human

SwissProt: Q6P9R4 Mouse

Unigene: 465761 Human

Unigene: 736818 Human

Unigene: 170461 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
情侣网站大黄网站 | 在线中文字幕亚洲第一 | 成 人 黄 色 免费 网站无毒 | 亚洲天堂AV免费在线观看 | 熟妇丰满videosxxxxx | 爆乳JK美女脱内衣裸体网站 | 麻豆精品传媒一二三区 | 又粗又大又黄的少妇毛片 | 日本不卡免费高清视频 | 成人H动漫精品一区二区 | 精品亚洲国产成AV人片传媒 | 特黄四级人牲片在线观看 | 久99re视频9在线观看 | 色婷婷色综合缴情网站 | 爱剪辑视频社区在线资源 | 一本到无码高清手机字幕在线播放 | а√在线中文网新版地址在线 | 最新国产精品自在自线发布 | 手机永久免费的AV在线电影网无码 | 国产一级特黄a大片99 | 高潮毛片无遮挡高清免费视频 | 欧美最猛性xxxxx亚洲精品 | 一本视频精品中文字幕 | 狂躁美女大BBBBBB视频U | 国产无遮挡无码视频在线观看不卡 | 亚洲字幕AV一区二区三区四区 | 国产精品亚洲欧美一区麻豆 | 亚洲中文无码永久免费 | 国产国语高清在线视频二区 | 色婷婷国产精品无码视频 | 亚洲国产精品一区二区三区在线观看 | 亚洲乱码高清午夜理论电影 | 最新中文字幕A片专区 | 亚洲欧洲另类春色校园小说 | 内射干少妇亚洲69XXX | 欧美日韩国产综合视频一区二区 | 国产精品久久久久久久久齐齐 | 国产又黄又爽无遮挡动态图 | 国产下药迷倒白嫩丰满美女BD | 国产精品国产三级国产AV麻豆 | 91热久久免费频精品动漫99 |