| 產(chǎn)品編號(hào) | bs-13459R-Gold |
| 英文名稱 | Rabbit Anti-GMP Synthase/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的谷氨酰胺轉(zhuǎn)移酶GMPS抗體 |
| 別 名 | GMPS; Glutamine amidotransferase; GMP synthase [glutamine hydrolyzing]; GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Gmps; GUAA_HUMAN; Guanine monphosphate synthetase; MLL/GMPS fusion protein. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 染色質(zhì)和核信號(hào) 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 77kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GMP Synthase |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq, Jul 2008]. Function: Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division. Subcellular Location: Cytoplasm. Tissue Specificity: Note=A chromosomal aberration involving GMPS is found in acute myeloid leukemias. Translocation t(3,11)(q25,q23) with MLL. Similarity: Contains 1 glutamine amidotransferase type-1 domain. Contains 1 GMP-binding domain. Database links: UniProtKB/Swiss-Prot: P49915.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
