亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
动漫精品视频一区二区三区,精品国产午夜福利在线观看
Rabbit Anti-GPR37/Cy3 Conjugated antibody (bs-13534R-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-13534R-Cy3
英文名稱 Rabbit Anti-GPR37/Cy3 Conjugated antibody
中文名稱 Cy3標(biāo)記的G蛋白偶聯(lián)受體37/帕金森相關(guān)內(nèi)皮素受體樣受體抗體
別    名 GPCR GPR37; EDNRBL; Endothelin B receptor like protein 1; Endothelin B receptor-like protein 1; Endothelin receptor type B like; ETBR LP 1; ETBR-LP-1; ETBRLP1; G protein coupled receptor 37; G protein coupled receptor 37 endothelin receptor type B like; Gpr37; GPR37_HUMAN; hET(B)R LP; hET(B)RLP; PAELR; Parkin associated endothelin receptor like receptor; Parkin-associated endothelin receptor-like receptor; Probable G protein coupled receptor 37; Probable G-protein coupled receptor 37; GPCR 37.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 67kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR37
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Pael receptor (Pael-R), also known as Parkin-associated endothelin receptor-like receptor, is a putative G protein-coupled transmembrane polypeptide. The gene that encodes Pael-R maps to chromosome 7q31. Pael-R belongs to family 1 of the G protein-coupled receptors and is mainly expressed in the brain. Pael-R interacts with Parkin, the gene product responsible for familial Parkinson’s disease.

Function:
Orphan receptor. May have a unique functional role in the central nervous system.

Subunit:
Forms a complex with PARK2, STUB1 and HSP70. The amount of STUB1 in the complex increases during ER stress. STUB1 promotes the dissociation of HSP70 from PARK2, thus facilitating PARK2-mediated GPR37 ubiquitination. Interacts with PACRG.

Subcellular Location:
Cell membrane. Endoplasmic reticulum membrane.

Tissue Specificity:
Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may lead to dopaminergic neuronal death in juvenile Parkinson disease (PDJ).

Post-translational modifications:
Ubiquitinated by PARK2 in the presence of UBE2E1 and UBE2L3 in the endoplasmic reticulum. The unfolded form is specifically ubiquitinated by SYVN1, which promotes its proteasomal degradation and prevents neuronal cell death.

DISEASE:
Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may lead to dopaminergic neuronal death in juvenile Parkinson disease (PDJ).

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 2861 Human

Entrez Gene: 14763 Mouse

Entrez Gene: 117549 Rat

Omim: 602583 Human

SwissProt: O15354 Human

SwissProt: Q9QY42 Mouse

SwissProt: Q9QYC6 Rat

Unigene: 731392 Human

Unigene: 409670 Mouse

Unigene: 28035 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
加勒比AV一本大道香蕉大在线 | 男女性潮高片无遮挡禁18 | 上海少妇高潮狂叫喷水了 | 人妻互换免费中文字幕网站 | 国产喷水1区2区3区咪咪爱AV | 最近中文字幕在线中文视频 | 日日夜夜免费精品视频 | 亚洲精品无码久久久久久久久 | 伊人狠狠丁香婷婷综合尤物 | 天天爽夜夜爽夜夜爽精品视频 | 日本夜爽爽一区二区三区 | 久久久人人爱AV高潮喷水 | 欧美透明丰满内衣内裤 | 无码国产亚洲日韩国精品视频一区二区三区 | 樱花草中文在线观看高清视频 | 国产黄A真人一级无码毛片一区二区三区 | 亚洲AV无码成人精品区东京热 | 免费一级毛片私人影院a行 99精产国品一二三产 | 国产午夜精品理论片小yo奈 | 全部在线播放免费毛片 | 女帝被扒开双腿疯狂输出 | 日日夜夜免费精品视频 | 韩日AV无码片一区二区三区 | 十八岁以下禁止观看的1000个网站 | 成人区人妻精品一区二区不卡视频 | 午夜欧美日韩精品久久久久久 | 久久综合色天天久久综合图片 | 免费A级毛片—亚洲一区二区久久69 | 国产美女裸体无遮挡免费视频高潮 | 给我免费播放片在线中国 | 班长让我坐在那个地方教我作业 | 国产黄A三级三级三级看三级 | 国内毛片毛片毛片毛片毛片毛片毛片毛片毛片毛片毛片毛片 | 亚洲中文字幕乱码免费播放 | 国产一级aa无码大片在线视频 | 亚洲一区二区三区乱码在线欧洲 | 成人免费精品网站在线观看影片 | 正在播放国产精品 | 黄色视频在线观看网站 | 精品国语对白清晰在线 | 日韩AV无码专区国产乱码 |