亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質(zhì)量反饋  關于我們  聯(lián)系我們
亚洲AV√最新天堂版资源地址在线官网,18禁裸乳无遮挡啪啪无码免费 ,高清少妇熟女一区二区
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-GPR37/Cy5.5 Conjugated antibody (bs-13534R-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-13534R-Cy5.5
英文名稱 Rabbit Anti-GPR37/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標記的G蛋白偶聯(lián)受體37/帕金森相關內(nèi)皮素受體樣受體抗體
別    名 GPCR GPR37; EDNRBL; Endothelin B receptor like protein 1; Endothelin B receptor-like protein 1; Endothelin receptor type B like; ETBR LP 1; ETBR-LP-1; ETBRLP1; G protein coupled receptor 37; G protein coupled receptor 37 endothelin receptor type B like; Gpr37; GPR37_HUMAN; hET(B)R LP; hET(B)RLP; PAELR; Parkin associated endothelin receptor like receptor; Parkin-associated endothelin receptor-like receptor; Probable G protein coupled receptor 37; Probable G-protein coupled receptor 37; GPCR 37.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經(jīng)生物學  信號轉(zhuǎn)導  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Rabbit, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 67kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR37
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Pael receptor (Pael-R), also known as Parkin-associated endothelin receptor-like receptor, is a putative G protein-coupled transmembrane polypeptide. The gene that encodes Pael-R maps to chromosome 7q31. Pael-R belongs to family 1 of the G protein-coupled receptors and is mainly expressed in the brain. Pael-R interacts with Parkin, the gene product responsible for familial Parkinson’s disease.

Function:
Orphan receptor. May have a unique functional role in the central nervous system.

Subunit:
Forms a complex with PARK2, STUB1 and HSP70. The amount of STUB1 in the complex increases during ER stress. STUB1 promotes the dissociation of HSP70 from PARK2, thus facilitating PARK2-mediated GPR37 ubiquitination. Interacts with PACRG.

Subcellular Location:
Cell membrane. Endoplasmic reticulum membrane.

Tissue Specificity:
Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may lead to dopaminergic neuronal death in juvenile Parkinson disease (PDJ).

Post-translational modifications:
Ubiquitinated by PARK2 in the presence of UBE2E1 and UBE2L3 in the endoplasmic reticulum. The unfolded form is specifically ubiquitinated by SYVN1, which promotes its proteasomal degradation and prevents neuronal cell death.

DISEASE:
Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may lead to dopaminergic neuronal death in juvenile Parkinson disease (PDJ).

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 2861 Human

Entrez Gene: 14763 Mouse

Entrez Gene: 117549 Rat

Omim: 602583 Human

SwissProt: O15354 Human

SwissProt: Q9QY42 Mouse

SwissProt: Q9QYC6 Rat

Unigene: 731392 Human

Unigene: 409670 Mouse

Unigene: 28035 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
久久久亚洲欧洲日产国码二区 | 成人免费视频在线观看 | 在线精品亚洲欧美日韩国产 | 高清视频黄色录像免费 | 九九精品免费观看在线 | 麻豆一区二区免费播放网站 | 欧美人与动牲交A精品 | 色婷五月综激情亚洲综合 | 探花口爆颜射乳交日韩 | **女人一级毛片免费视频观看 | 午夜不卡久久精品无码免费 | 亚洲综合久久精品无码色欲 | 欧美日韩高清一区二区三区 | 无码中文字幕拍偷乱偷精品 | 欧美自拍亚洲精品动图 | 菠萝菠萝蜜影视在线观看小草免费 | 亚洲高清在线精品一区 | 欧美日韩乱国产无遮挡 | 91久久精品日日躁夜夜躁欧美 | 亚瑟TV私人网站 | 欧美日韩精品一区二区在线播放蜜臀 | 国产福利一区二区三区在线观看 | ww男人的天堂视频在线观看 | 日韩超碰人人爽人人做人人天 | 色姑娘久久综合网天天 | 51吃瓜中心-吃最新最真的瓜 | 在线中文字幕亚洲第一 | 国产午夜男女爽爽爽爽爽 | 人妻无码专区一专区二专区三 | 短篇公交车高H肉辣全集目录 | 日韩精品人妻AV一区二区三区 | 国产午夜无码精品免费看性色 | 少妇人妻AV毛片在线看 | 久久久精品中文字幕麻豆发布 | 91精品国自产在线观看 | 97夜夜澡人人爽人人喊中国片 | 无码人妻丰满熟妇精品区 | 久久久99精品免费观看 | 91天堂最新在线观看 | 国产又湿又黄又硬又刺激视频 | 亚洲日韩国产成在线发布一区二区三区 |