亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
无套内射在线观看THEPORN,男人的好看免费观看在线视频
Rabbit Anti-GPR37/APC Conjugated antibody (bs-13534R-APC)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-13534R-APC
英文名稱(chēng) Rabbit Anti-GPR37/APC Conjugated antibody
中文名稱(chēng) APC標(biāo)記的G蛋白偶聯(lián)受體37/帕金森相關(guān)內(nèi)皮素受體樣受體抗體
別    名 GPCR GPR37; EDNRBL; Endothelin B receptor like protein 1; Endothelin B receptor-like protein 1; Endothelin receptor type B like; ETBR LP 1; ETBR-LP-1; ETBRLP1; G protein coupled receptor 37; G protein coupled receptor 37 endothelin receptor type B like; Gpr37; GPR37_HUMAN; hET(B)R LP; hET(B)RLP; PAELR; Parkin associated endothelin receptor like receptor; Parkin-associated endothelin receptor-like receptor; Probable G protein coupled receptor 37; Probable G-protein coupled receptor 37; GPCR 37.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 67kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR37
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Pael receptor (Pael-R), also known as Parkin-associated endothelin receptor-like receptor, is a putative G protein-coupled transmembrane polypeptide. The gene that encodes Pael-R maps to chromosome 7q31. Pael-R belongs to family 1 of the G protein-coupled receptors and is mainly expressed in the brain. Pael-R interacts with Parkin, the gene product responsible for familial Parkinson’s disease.

Function:
Orphan receptor. May have a unique functional role in the central nervous system.

Subunit:
Forms a complex with PARK2, STUB1 and HSP70. The amount of STUB1 in the complex increases during ER stress. STUB1 promotes the dissociation of HSP70 from PARK2, thus facilitating PARK2-mediated GPR37 ubiquitination. Interacts with PACRG.

Subcellular Location:
Cell membrane. Endoplasmic reticulum membrane.

Tissue Specificity:
Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may lead to dopaminergic neuronal death in juvenile Parkinson disease (PDJ).

Post-translational modifications:
Ubiquitinated by PARK2 in the presence of UBE2E1 and UBE2L3 in the endoplasmic reticulum. The unfolded form is specifically ubiquitinated by SYVN1, which promotes its proteasomal degradation and prevents neuronal cell death.

DISEASE:
Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may lead to dopaminergic neuronal death in juvenile Parkinson disease (PDJ).

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 2861 Human

Entrez Gene: 14763 Mouse

Entrez Gene: 117549 Rat

Omim: 602583 Human

SwissProt: O15354 Human

SwissProt: Q9QY42 Mouse

SwissProt: Q9QYC6 Rat

Unigene: 731392 Human

Unigene: 409670 Mouse

Unigene: 28035 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
日日躁夜夜躁狠狠久久AV | 成 人片 黄 色 大 片 | 日韩欧无码一区二区三区免费不卡 | 中文字幕一区二区精品区 | 国产精品久久久精品无码 | 女人脱精光让人桶爽了 | 穿着白丝被强行侵犯漫画 | 国产成人精品自产拍在线观看 | 一级成人欧美一区在线观看 | 永久免费精品精品永久-夜色 | 在线观看白嫩美乳e奶大胸美女 | 欧美精品免费观看二区 | 91免费精品国自产拍在线不卡 | 亚洲av无码一区二区三区人妖 | 亚洲婷婷国产精品电影人久久 | 欧美日韩人妻精品一区在线 | 80年代十大欧美成人片 | 精品国产午夜肉伦伦影院 | 亚洲中文字幕在线一区播放 | 亚洲成年人免费网站 | 久久婷婷97人妻无码狠狠综合久久久久综合 | 调教我的妺妺H肉YIN荡视频 | 欧美一级高清AAA片免费观看 | 欧美亚洲国产精品久久高清 | 人妻体内射精一区二区三四 | 黄成人app网站在线看 | 欧美性生活视频免费播放网址大全观看 | 欧美日韩综合精品二区 | 欧美一级毛片在播放免费 | 亚州日本乱码一区二区三区 | 国产伦精品一区二区三区免.费 | 日韩欧美一区二区中文字幕 | 又黄又爽又无遮挡在线观看免费 | a级高清观看视频在线看 | 四虎2021国产最新地址 | 成人MV射精无打码视频 | 污全彩肉肉无遮挡彩色 | 国产精品毛片一级久久 | 色婷婷色综合缴情网站 | 狠狠躁夜夜躁人人爽天天69 | 亚洲精品无码天堂AV |