亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
国产三级视频在线,一级毛片在线看在线播放,国产午夜三级一区二区三
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Claudin 16/Cy5 Conjugated antibody (bs-13752R-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13752R-Cy5
英文名稱 Rabbit Anti-Claudin 16/Cy5 Conjugated antibody
中文名稱 Cy5標記的緊密連接蛋白16抗體
別    名 Claudin 16; Claudin-16; CLD16_HUMAN; CLDN 16; Cldn16; Paracellin 1; Paracellin-1; PCLN-1; PCLN 1; PCLN1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  細胞粘附分子  內皮細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Claudin 16
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Tight junctions mediate the regulation of the paracellular pathway between epithelial and endothelial cells. They form close connections to eliminate the extracellular space and regulate the flow of solutes between cells. The human gene PCLN-1 (paracellin-1) is related to the claudin family of integral membrane proteins, which localize to tight junctions. PCLN-1 contains four transmembrane domains and intracellular amino and carboxy termini, characteristic of the other claudin family members, and is detected only at the tight junctions of kidney tissue. PCLN-1 forms an intercellular pore and controls the resorption of magnesium and calcium in the thick ascending limb of Henle (TAL). Mutations in PCLN-1 cause renal magnesium wasting, which may contribute to a rare autosomal recessive disease, renal hypomagnesemia with hypercalciuria and nephrocalcinosis.

Function:
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in paracellular magnesium reabsorption. Required for a selective paracellular conductance. May form, alone or in partnership with other constituents, an intercellular pore permitting paracellular passage of magnesium and calcium ions down their electrochemical gradients. Alternatively, it could be a sensor of magnesium concentration that could alter paracellular permeability mediated by other factors.

Subcellular Location:
Cell junction; tight junction. Cell membrane.

Tissue Specificity:
Kidney-specific, including the thick ascending limb of Henle (TAL).

DISEASE:
Defects in CLDN16 are the cause of hypomagnesemia type 3 (HOMG3) [MIM:248250]; also known as familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC). HOMG3 is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis. Recurrent urinary tract infections and kidney stones are often observed. In spite of hypercalciuria, patients do not show hypocalcemia.

Similarity:
Belongs to the claudin family.

Database links:

Entrez Gene: 10686 Human

Entrez Gene: 114141 Mouse

Entrez Gene: 155268 Rat

Omim: 603959 Human

SwissProt: Q9Y5I7 Human

SwissProt: Q14BW2 Mouse

SwissProt: Q925N4 Mouse

SwissProt: Q91Y55 Rat

Unigene: 251391 Human

Unigene: 275205 Mouse

Unigene: 43852 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
成人网站在线进入爽爽爽 | 欧美亚洲另类日韩图片区 | 成人免费毛片AAAAAA片 | 狼人大香伊蕉国产WWW亚洲 | 亚州**色毛片免费观看 | 亚洲精品免费视频观看视频 | √天堂中文在线最新版 | 精品21国产成人综合网在线 | 狠狠色丁香婷婷综合 | 国产AV午夜精品一区二区入口 | 国产一区二区精品久久岳 | 特级做a爰片毛片免费看 | gvg454真实性教育在线播放 | 国产www在线观看 | 完全着衣の爆乳お姉さんが | 亚洲欧美在线观看H片 | 久久精品国产9久久综合 | 欧美中文字幕一区二区三区 | 国产午夜一级鲁丝片 | 亚洲精品V天堂中文字幕 | 国产一区二区三区AV天堂 | 国产偷国产偷亚州清高APP | 国产精品永久在线 | 2019国自产拍精品 | 无码人妻免费一区二区三区 | 内射干少妇亚洲69XXX | 小龙女玉足娇喘蕾丝湿润 | 国产免费看插插插视频 | 国产黑丝一区二区 | 免费少妇A级毛片野外大战 亚洲精品高清一二区久久 精品欧美一区二区三区成人片在线 | 国产手机在线国内精品 | 精品人妻少妇久久久AV | 中出人妻中文字幕无码 | 人妻互换免费中文字幕 | 涩涩视频在线播放 | 精品一区二区三区无码av孕妇 | 欧美一级做a爰片免费 | 韩日美无码精品无码 | 国产欧美精品一区二区三区-老狼 | 高潮毛片无遮挡高清免费视频 | 777久久精品一区二区三区无码 |