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Rabbit Anti-NCALD/Gold Conjugated antibody (bs-14442R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-14442R-Gold
英文名稱 Rabbit Anti-NCALD/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的神經(jīng)鈣蛋白NCALD抗體
別    名 MGC33870; MGC74858; NCALD; NCALD_HUMAN; Neurocalcin delta; Neurocalcin-delta.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  結(jié)合蛋白  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Cow, Rabbit, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NCALD
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Function:
May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions.

Tissue Specificity:
Retina, cerebrum, cerebellum, brain stem, spinal cord, testis, ovary and small intestine.

Similarity:
Belongs to the recoverin family.
Contains 4 EF-hand domains.

Database links:

Entrez Gene: 83988 Human

Entrez Gene: 281940 Cow

Entrez Gene: 52589 Mouse

Entrez Gene: 553106 Rat

Omim: 606722 Human

SwissProt: P61602 Cow

SwissProt: P61601 Human

SwissProt: Q91X97 Mouse

SwissProt: Q5PQN0 Rat

Unigene: 492427 Human

Unigene: 680132 Human

Unigene: 283370 Mouse

Unigene: 13744 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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