亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
亚洲一级毛片免观看,欧美日韩另类在线观看视频
Rabbit Anti-CENPE/RBITC Conjugated antibody (bs-8846R-RBITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-8846R-RBITC
英文名稱 Rabbit Anti-CENPE/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標(biāo)記的著絲粒相關(guān)蛋白E抗體
別    名 CENP E; Centromere associated protein E; Centromere autoantigen E (312kD); Centromere autoantigen E; Centromere protein E 312kDa; Centromere protein E; Centromeric protein E; KIF10; Kinesin family member 10; Kinesin related protein; Kinesin related protein CENPE; PPP1R61; Protein phosphatase 1, regulatory subunit 61.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞分化  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 316kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CENPE
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Nov 2014]

Function:
Essential for the maintenance of chromosomal stability through efficient stabilization of microtubule capture at kinetochores. Plays a key role in the movement of chromosomes toward the metaphase plate during mitosis. Is a slow plus end-directed motor whose activity is essential for metaphase chromosome alignment. Couples chromosome position to microtubule depolymerizing activity. The highly processive microtubule-dependent motor activity of CENPE serves to power chromosome congression and provides a flexible, motile tether linking kinetochores to dynamic spindle microtubules. Necessary for the mitotic checkpoint signal at individual kinetochores to prevent aneuploidy due to single chromosome loss. Required for the efficient recruitment of BUBR1, MAD1 and MAD2 to attached and newly unattached kinetochores. Stimulates mammalian BUBR1 kinase activity. Accumulates just before mitosis at the G2 phase of the cell cycle.

Subunit:
Monomer. Interacts with CENPF, SEPT7, KIF18A, BUB1B kinase and PRC1. Interacts with NUF2; this interaction determines kinetochore localization. Interacts with SKAP; this interaction greatly favors SKAP binding to microtubules.

Subcellular Location:
Associates with kinetochores during congression, relocates to the spindle midzone at anaphase, and is quantitatively discarded at the end of the cell division.

Post-translational modifications:
The C-terminal inhibitory domain is phosphorylated. Phosphorylation relieves autoinhibition of the kinetochore motor (By similarity

Similarity:
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Contains 1 kinesin motor domain.

Database links:

Entrez Gene: 1062 Human

Omim: 117143 Human

SwissProt: Q02224 Human

Unigene: 75573 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产午夜精品一区二区三区软件 | 国产a级三级三级成人国产一级婬片 | 99精品无人区乱码1区2区3区 | 免费在线观看成人电影 | 欧美精品视频在线观看视频 | 在线高清国语成人网站 | 久久精品这里热有精品6 | 美女尿口羞羞视频 | 深夜久久AAAAA级毛片免费看 | 无码的免费不卡毛片视频 | 二区久久久国产AV色 | 伊人婷婷涩六月丁香七月 | 国产欧美日韩一区二区搜索 | WWW久久只有这里有精品 | 国产日韩欧美丝袜一区二区 | 日韩一级精品久久久久 | 欧美性猛交AAAA片黑人 | 国产综合色香蕉精品五夜婷 | 日韩精品福利视频一区二区三区 | 精品久久久久久久一区二区 | 亚洲综合网国产精品一区 | 伊人久久精品中文字幕 | 菠萝菠萝蜜影视在线观看小草免费 | 欧美日韩国产综合视频一区二区 | 一色屋精品亚洲香蕉网站 | 国产精品日产欧美久久久 | 国产猛男猛女超爽免费视频 | 2021久久精品免费观看 | 国产精品爱啪在线播放 | 精品丝袜久久久久人妻 | 快穿之浪荡H啪肉NP文肉BL | 日韩欧无码一区二区三区免费不卡 | 麻豆文化传媒精品1区2区3区 | 国产一级特黄aaa大片 | 亚洲欧洲性色精品一区二区三区在线观看 | 日韩久久久久久无码精品 | 动漫AV网站免费观看 | 一级黄色网站在线观看 | 亚洲午夜尤物中文字幕在线 | 欧美肥胖老太vidio在线视频 | 亚洲调教自慰喷水AV无码 |