亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日本少妇AA一级特黄大片,日本高清在线天码一区播放
Rabbit Anti-CENPE/BF647 Conjugated antibody (bs-8846R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-8846R-BF647
英文名稱 Rabbit Anti-CENPE/BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的著絲粒相關(guān)蛋白E抗體
別    名 CENP E; Centromere associated protein E; Centromere autoantigen E (312kD); Centromere autoantigen E; Centromere protein E 312kDa; Centromere protein E; Centromeric protein E; KIF10; Kinesin family member 10; Kinesin related protein; Kinesin related protein CENPE; PPP1R61; Protein phosphatase 1, regulatory subunit 61.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  染色質(zhì)和核信號  信號轉(zhuǎn)導(dǎo)  細(xì)胞分化  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 316kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CENPE
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Nov 2014]

Function:
Essential for the maintenance of chromosomal stability through efficient stabilization of microtubule capture at kinetochores. Plays a key role in the movement of chromosomes toward the metaphase plate during mitosis. Is a slow plus end-directed motor whose activity is essential for metaphase chromosome alignment. Couples chromosome position to microtubule depolymerizing activity. The highly processive microtubule-dependent motor activity of CENPE serves to power chromosome congression and provides a flexible, motile tether linking kinetochores to dynamic spindle microtubules. Necessary for the mitotic checkpoint signal at individual kinetochores to prevent aneuploidy due to single chromosome loss. Required for the efficient recruitment of BUBR1, MAD1 and MAD2 to attached and newly unattached kinetochores. Stimulates mammalian BUBR1 kinase activity. Accumulates just before mitosis at the G2 phase of the cell cycle.

Subunit:
Monomer. Interacts with CENPF, SEPT7, KIF18A, BUB1B kinase and PRC1. Interacts with NUF2; this interaction determines kinetochore localization. Interacts with SKAP; this interaction greatly favors SKAP binding to microtubules.

Subcellular Location:
Associates with kinetochores during congression, relocates to the spindle midzone at anaphase, and is quantitatively discarded at the end of the cell division.

Post-translational modifications:
The C-terminal inhibitory domain is phosphorylated. Phosphorylation relieves autoinhibition of the kinetochore motor (By similarity

Similarity:
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Contains 1 kinesin motor domain.

Database links:

Entrez Gene: 1062 Human

Omim: 117143 Human

SwissProt: Q02224 Human

Unigene: 75573 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
免费永久观看美女视频网站网址 | 亚洲AV日韩Av永久无码破 | 亚洲精品国产日韩无码AV永久免费网 | 国产精品一区二区AV交换 | 成熟丰满女人免费视频 | 久久久久久免费一区二区三区 | 国产精品日本一区二区在线播放 | fuli.su黑料正能量入口 | 亚洲中文乱码AV网站 | 久久久久免费看精品国产成人一区二区三区 | 久久久久国产美女免费网站 | 精品久久久久久无码人妻热蜜芽 | 都市人妻古典武侠另类校园 | 成全动漫视频在线观看完整版 | 激情欧美日韩一区二区 | 久久人人爽人人爽人人片AV不 | 国产91麻豆免费观看 | 亚欧色一区W666天堂 | 精品一卡2卡三卡4卡乱码毛1 | 丰满护士巨好爽好大乳小说 | 日韩久久免费影院观看 | 欧美日韩一区在线观看 | 国产欧美日韩亚洲精品区 | 国产乱人伦偷精品视频免下载 | 美女扒开内裤羞羞网站 | 日韩精品一区二区三区免费视频 | 狠狠色综合久久久久尤物 | 狠狠色综合7777久夜色撩人 | 国产成a人片在线观看视频 女人赤裸裸正面下身照片 女人脱精光让人桶爽了 | 精品国产乱码久久久久久浪潮小说 | 日本丰满熟妇被捏出奶水 | 两女互慰AV高潮喷水在线观看 | 国产麻豆精品精东影业AV网站 | 久久黄色免费网站 | 亚洲日韩久久精品无码AV | 欧美激情一区二区三区蜜桃视频 | 午夜福利免费一区二区小说 | 人妻体内射精一区二区 | 精品人妻少妇一级毛片免费 | 色欲久久久久久综合网精品 | 亚洲中文字幕在线观看 |