亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
风情艳主调教朋友圈变态,国产精品毛片a∨一区二区三区,91最新在线视频
Rabbit Anti-CENPE/PE-Cy7 Conjugated antibody (bs-8846R-PE-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-8846R-PE-Cy7
英文名稱 Rabbit Anti-CENPE/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標(biāo)記的著絲粒相關(guān)蛋白E抗體
別    名 CENP E; Centromere associated protein E; Centromere autoantigen E (312kD); Centromere autoantigen E; Centromere protein E 312kDa; Centromere protein E; Centromeric protein E; KIF10; Kinesin family member 10; Kinesin related protein; Kinesin related protein CENPE; PPP1R61; Protein phosphatase 1, regulatory subunit 61.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞分化  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 316kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CENPE
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Nov 2014]

Function:
Essential for the maintenance of chromosomal stability through efficient stabilization of microtubule capture at kinetochores. Plays a key role in the movement of chromosomes toward the metaphase plate during mitosis. Is a slow plus end-directed motor whose activity is essential for metaphase chromosome alignment. Couples chromosome position to microtubule depolymerizing activity. The highly processive microtubule-dependent motor activity of CENPE serves to power chromosome congression and provides a flexible, motile tether linking kinetochores to dynamic spindle microtubules. Necessary for the mitotic checkpoint signal at individual kinetochores to prevent aneuploidy due to single chromosome loss. Required for the efficient recruitment of BUBR1, MAD1 and MAD2 to attached and newly unattached kinetochores. Stimulates mammalian BUBR1 kinase activity. Accumulates just before mitosis at the G2 phase of the cell cycle.

Subunit:
Monomer. Interacts with CENPF, SEPT7, KIF18A, BUB1B kinase and PRC1. Interacts with NUF2; this interaction determines kinetochore localization. Interacts with SKAP; this interaction greatly favors SKAP binding to microtubules.

Subcellular Location:
Associates with kinetochores during congression, relocates to the spindle midzone at anaphase, and is quantitatively discarded at the end of the cell division.

Post-translational modifications:
The C-terminal inhibitory domain is phosphorylated. Phosphorylation relieves autoinhibition of the kinetochore motor (By similarity

Similarity:
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Contains 1 kinesin motor domain.

Database links:

Entrez Gene: 1062 Human

Omim: 117143 Human

SwissProt: Q02224 Human

Unigene: 75573 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产国语特级**a毛片 | 免费看一级一级人妻片 | 久久久久亚洲精品影视 | 成人无码片黄网站A毛片免费 | 免费人成a大片在线播放 | 天堂网在线最新版www资源网 | 中文字幕在线免费观看视频 | 精产国蘑菇品一二三产品区 | 成人免费视频在线观看 | 先峰中文字幕一二三区 | 精品国产福利一区二区在线 | 2020国产欧洲精品视频 | 乱欧人与牲口杂交暴力狂 | 在线观看日本污污ww网站 | 欧洲亚洲日韩中文字幕首页 | 亚洲美女又黄又爽在线观看 | 少妇自慰白浆一区二区 | 欧美日本韩国一二区视频 | 一区二区三区在线播放 | 在线观看亚洲一区二区 | 亚洲欧美日韩在线观看 | 亚洲国产一区二区三区AV | 欧美一区二区三区播放 | 中文字幕视频在线观看 | 久久久精品国产亚洲AV无码 | 又污又黄又无遮挡网站 | 日本一区二区三区在线观看网站 | 日产精品美女久久久网站大全 | 囯产精品一品二区三区 | 日韩高清成片免费视频 | 精品精品国产三级A∨在线 **色毛片免费观看 色欲日本人妻久久久久久综合 | 内地级A艳片高清免费播放 国产精品无码不卡系列在线 | 国产小视频在线高清播放 | 一个色综合国产色综合 | 玩白嫩少妇小泬高潮18P | 精品91自产拍在线观看二区 | 野花视频在线观看高清免费完整版 | 啊灬啊灬啊灬快灬少妇 | 精品熟女少妇AV免费观看 | 日韩视频在线精品视频免费观看 | 对白脏话肉麻粗话视频 |