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Rabbit Anti-FGD6/BF647 Conjugated antibody (bs-16082R-BF647)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-16082R-BF647
英文名稱 Rabbit Anti-FGD6/BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的FGD6蛋白抗體
別    名 FYVE, RhoGEF and PH domain containing protein 6; ZFYVE24; FGD6_HUMAN; Zinc finger FYVE domain containing protein 24.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 161kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FGD6
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
FGD6 is a 1,430 amino acid cytoplasmic protein that belongs to the FGD family and exists as two alternatively spliced isoforms. Thought to activate Cdc42 by exchanging bound GDP for free GTP, FGD6 is also implicated in maintenance of the actin cytoskeleton and regulating cell shape. Encoded by a gene that maps to human chromosome 12q22, FGD6 contains one FYVE-type zinc finger, two PH domains and a single DH (DBL-homology) domain.

Function:
FGD6 may activate CDC42 by exchanging bound GDP for free GTP. It may also play a role in regulating the actin cytoskeleton and cell shape. There are two isoforms.

Subcellular Location:
Cytoplasm (Probable). Cytoplasm, cytoskeleton (Probable).

Database links:

Entrez Gene: 55785 Human

SwissProt: Q6ZV73 Human

Unigene: 506381 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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