亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
最新国产麻豆精品,野花香日本大全免费观看,久久夜色国产亚洲色欲AV
Rabbit Anti-TPA/Biotin Conjugated antibody (bs-17162R-Bio)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-17162R-Bio
英文名稱 Rabbit Anti-TPA/Biotin Conjugated antibody
中文名稱 生物素標(biāo)記的組織型纖溶酶原激活蛋白抗體
別    名 TPA Tissue Plasminogen Activator; Alteplase; DKFZp686I03148; Plasminogen activator tissue; Plasminogen activator tissue type; PLAT; Reteplase; t PA; T Plasminogen Activator; t-PA; T-plasminogen activator; Tissue plasminogen activator (t PA); Tissue type plasminogen activator; Tissue-type plasminogen activator chain B; tPA; TPA_HUMAN; TPA1.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  新陳代謝  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 59kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Tissue-type plasminogen activator chain B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Function:
Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Play a direct role in facilitating neuronal migration.

Subcellular Location:
Secreted > extracellular space.

Tissue Specificity:
Synthesized in numerous tissues (including tumors) and secreted into most extracellular body fluids, such as plasma, uterine fluid, saliva, gingival crevicular fluid, tears, seminal fluid, and milk.

Post-translational modifications:
The single chain, almost fully active enzyme, can be further processed into a two-chain fully active form by a cleavage after Arg-310 catalyzed by plasmin, tissue kallikrein or factor Xa.
Differential cell-specific N-linked glycosylation gives rise to two glycoforms, type I (glycosylated at Asn-219) and type II (not glycosylated at Asn-219). The single chain type I glycoform is less readily converted into the two-chain form by plasmin, and the two-chain type I glycoform has a lower activity than the two-chain type II glycoform in the presence of fibrin. N-glycosylation of Asn-152; the bound oligomannosidic glycan is involved in the interaction with the mannose receptor.
Characterization of O-linked glycan was studied in Bowes melanoma cell line.

DISEASE:
Note=Increased activity of TPA results in increased fibrinolysis of fibrin blood clots that is associated with excessive bleeding. Defective release of TPA results in hypofibrinolysis that can lead to thrombosis or embolism.

Similarity:
Belongs to the peptidase S1 family.
Contains 1 EGF-like domain.
Contains 1 fibronectin type-I domain.
Contains 2 kringle domains.
Contains 1 peptidase S1 domain.

Database links:

Entrez Gene: 5327 Human

Entrez Gene: 18791 Mouse

Entrez Gene: 25692 Rat

Omim: 173370 Human

SwissProt: P00750 Human

SwissProt: P11214 Mouse

SwissProt: P19637 Rat

Unigene: 491582 Human

Unigene: 154660 Mouse

Unigene: 107102 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
国产精品国产馆在线真实露脸 | 国产欧美一区二区精品性色超碰 | 纯肉高H肉辣浪荡NP论J | 老汉扛起娇妻玉腿进入 | 成片人免费观看一级A片 | 强插女教师AV在线 | 国产又湿又黄又硬又刺激视频 | 小说区 图片区色 综合区 | 国产精品视频第一区二区三区 | 国产精品1000夫妇激情啪发布 | 999久久久免费精品国产 | 好爽别插了无码视频 | 无套内射在线观看THEPORN | 亚洲日韩国产成在线发布一区二区三区 | 欧美成人免费高清二区三区 | 特级做a爰片毛片免线看在线 | 黑白配黑粗硬大疯狂乱叫 | 97人人爽人人爽爽人人一区二区 | 欧美一区二区三区红桃小说 | 黃色AV片三級三級三級免费看 | 成年免费A级毛片免费看无码 | 班长让我坐在那个地方教我作业 | 日欧一片内射va在线影院 | 国产黄片高清无码在线观看 | 无码人妻精品一区二区蜜桃色 | 丰满爆乳肉感一区二区三区 | 激情aa视频试看免费 | 亚洲婷婷国产精品电影人久久 | 日韩精品无码一区二区中文字幕 | 精品1区2区3区产品乱码 | 国产精品电影久久 | 国产精品免费一级在线观看 | 日日夜夜免费精品视频 | 欧美色精品视频在线观看九 | 公的大龟慢慢挺进我的体内视频 | 欧美日韩乱国产无遮挡 | 国内久经典AAAAA片 | 精品人妻少妇一级毛片免费 | 最近高清中文字幕无吗免费看 | 无码人妻免费—区二区三 | 一二三四视频免费社区5 |