亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
扒开老师大腿猛进AAA片软件 ,国产午夜片无码区在线观看爱情网
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-TPA/AP Conjugated antibody (bs-17162R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-17162R-AP
英文名稱 Rabbit Anti-TPA/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的組織型纖溶酶原激活蛋白抗體
別    名 TPA Tissue Plasminogen Activator; Alteplase; DKFZp686I03148; Plasminogen activator tissue; Plasminogen activator tissue type; PLAT; Reteplase; t PA; T Plasminogen Activator; t-PA; T-plasminogen activator; Tissue plasminogen activator (t PA); Tissue type plasminogen activator; Tissue-type plasminogen activator chain B; tPA; TPA_HUMAN; TPA1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細胞生物  新陳代謝  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 59kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Tissue-type plasminogen activator chain B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Function:
Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Play a direct role in facilitating neuronal migration.

Subcellular Location:
Secreted > extracellular space.

Tissue Specificity:
Synthesized in numerous tissues (including tumors) and secreted into most extracellular body fluids, such as plasma, uterine fluid, saliva, gingival crevicular fluid, tears, seminal fluid, and milk.

Post-translational modifications:
The single chain, almost fully active enzyme, can be further processed into a two-chain fully active form by a cleavage after Arg-310 catalyzed by plasmin, tissue kallikrein or factor Xa.
Differential cell-specific N-linked glycosylation gives rise to two glycoforms, type I (glycosylated at Asn-219) and type II (not glycosylated at Asn-219). The single chain type I glycoform is less readily converted into the two-chain form by plasmin, and the two-chain type I glycoform has a lower activity than the two-chain type II glycoform in the presence of fibrin. N-glycosylation of Asn-152; the bound oligomannosidic glycan is involved in the interaction with the mannose receptor.
Characterization of O-linked glycan was studied in Bowes melanoma cell line.

DISEASE:
Note=Increased activity of TPA results in increased fibrinolysis of fibrin blood clots that is associated with excessive bleeding. Defective release of TPA results in hypofibrinolysis that can lead to thrombosis or embolism.

Similarity:
Belongs to the peptidase S1 family.
Contains 1 EGF-like domain.
Contains 1 fibronectin type-I domain.
Contains 2 kringle domains.
Contains 1 peptidase S1 domain.

Database links:

Entrez Gene: 5327 Human

Entrez Gene: 18791 Mouse

Entrez Gene: 25692 Rat

Omim: 173370 Human

SwissProt: P00750 Human

SwissProt: P11214 Mouse

SwissProt: P19637 Rat

Unigene: 491582 Human

Unigene: 154660 Mouse

Unigene: 107102 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
日韩精品人妻AV一区二区三区 | 小骚妇下面水多要插视频 | 黄色链接在线观看 | 日本aa免费电影 | 久久综合九色综合网站 | 国产高清国内精品福利色噜噜 | 国产乱码一区二区三区 | 白丝校花 让我C在线观看91 | 99久久免费国产精品特黄 | 丰满少妇高潮惨叫久久久久 | 色豆豆永久免费网站 | 国产欧美一区二区精品仙草咪 | 少妇野外一级内射婬片免费放 | 亚洲综合另类欧美久久久久精品 | 亚洲国产欧美经典三级 | 91国语精品自产拍在线观看性色 | 公翁搡一晚上两次 | 在线A亚洲老鸭窝天堂AV高清 | 精品日本亚洲一区二区三区 | 好黄好猛好爽好痛的视频 | 无码人妻AⅤ一区二区三区夏目 | 毛av毛aⅴ毛aaa正片 | 欧美性生活视频免费播放网址大全观看 | 国产性自爱拍偷在在线播放 | 午夜色大片在线观看 | 2019香蕉在线观看直播视频 | 国产精品视频一区二区猎奇 | 国产在线观看www | 亚洲AV无码精品蜜桃 | 欧美野性肉体狂欢大派对 | 五月天丁香婷深爱综合 | 大学生一级毛片全黄真人无码 | 日韩欧美视频一区 | 亚洲一区二区三区女厕偷拍 | 人善之交Z0OZO0D0G人善 | 最近中文在线字幕在线观看 | 成全视频免费高清观看在线 | 狠狠色综合7777夜色撩人久 | 男女高潮嘿咻激烈爱爱动态图 | 亚洲精品无码久久久久 | 永久免费一级av毛片网站 |