亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产一区二区无码蜜芽精品,欧美又大又粗又硬BBBBB小说
Rabbit Anti-hnRNP D/AUF1/Cy5.5 Conjugated antibody (bs-17331R-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-17331R-Cy5.5
英文名稱 Rabbit Anti-hnRNP D/AUF1/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標(biāo)記的異質(zhì)核核糖核蛋白AUF1抗體
別    名 ARE binding protein AUFI type A; AU-rich element RNA-binding protein 1; AUF; AUF1; AUF1A; Heterogeneous nuclear ribonucleoprotein D0; hnRNP D; hnRNP D0; hnRNPD; hnRNPD0; HNRPD; HNRPD_HUMAN; P37.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  結(jié)合蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Mouse, Rat, Dog, Pig, Cow, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human hnRNP D/AUF1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008]

Function:
Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.

Subcellular Location:
Nucleus. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes.

Post-translational modifications:
Arg-345 is dimethylated, probably to asymmetric dimethylarginine.
Methylated by PRMT1, in an insulin-dependent manner. The PRMT1-mediated methylation regulates tyrosine phosphorylation.

Similarity:
Contains 2 RRM (RNA recognition motif) domains.

Database links:

Entrez Gene: 3184 Human

Entrez Gene: 11991 Mouse

Entrez Gene: 79256 Rat

GenBank: NP_112738.1 Human

Omim: 601324 Human

SwissProt: Q14103 Human

SwissProt: Q60668 Mouse

SwissProt: Q9JJ54 Rat

Unigene: 480073 Human

Unigene: 150231 Mouse

Unigene: 94022 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
97色伦图片97色伦图影院久久 | 豪妇荡乳1一5潘金莲2 | 中国一级毛片在线观看 | 国产人成无码视频在线1000 | 欧美午夜艳片欧美精品 | 小宝极品内射国产在线 | 欧美日韩无线码免费播放器 | 欧美在线成人免费观看网站 | 内地级A艳片高清免费播放 国产精品无码不卡系列在线 | 999视频在线观看 | 国产精品一区二区不卡的视频 | 欧美日韩国产免费一区二区三区 | 一级a免一级a做免费线看内裤 | 国产成人无码精品久久久APP | 亚洲阿v天堂网2019无码 | 国产无套内射又大又猛又粗又爽 | 国产成人 亚洲 欧洲在线 | 国产深夜福利在线观看网站 | 欧美成人se01短视频在线看 | 久久亚洲精品中文字幕 | 96在线看片免费视频国产 | 大尺度很黄很肉的小说 | 婷婷无套内射影院 | 无码人妻精品一区二区三区千菊 | 公么大龟弄得我好舒服秀婷视频 | 日日噜噜噜夜夜爽爽狠狠 | 无码人妻精品一区二区中文 | 久久97久久精品免费观看黑人 | 精品性影院一区二区三区内射 | 亚洲国产成人久久综合一区77 | 国产精品久久久久久 | 亚洲女精品一区二区三区 | 欧美国产综合日韩一区二区 | 亚洲欧美日韩一区二区在线观看 | 欧美三级片a片在线观看 | 久久久久久成人毛片免费看 | 性无码免费一区二区三区 | 娇妻在客厅被朋友玩得呻吟漫画 | 91人人人玩人人妻精品99 | 在线观看亚洲AV无码每日更新 | 日本特级婬片a片免费手机版 |