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Rabbit Anti-MOG1/BF555 Conjugated antibody (bs-17704R-BF555)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-17704R-BF555
英文名稱 Rabbit Anti-MOG1/BF555 Conjugated antibody
中文名稱 BF555標(biāo)記的Ran結(jié)合蛋白MOG1抗體
別    名 DKFZp686F02139; homolog of yeast MOG1; HSPC165; HSPC236; likely ortholog of mouse RAN guanine nucleotide release factor; MGC110973; MOG 1; MOG1; MOG1 homolog; MOG1_HUMAN; RAN guanine nucleotide release factor; Ran-binding protein MOG1; RANGNRF; RANGRF.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 心血管  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  結(jié)合蛋白  G蛋白信號(hào)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MOG1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1.5 cardiac sodium channel in human. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]

Function:
May regulate the intracellular trafficking of RAN. In cardiac cells seems to regulate the cell surface localization of SCN5A.

Subunit:
Monomer (By similarity). Interacts with RAN, RAN-GTP and RAN-GDP. Forms a complex with RAN-GTP and RANBP1 (By similarity). Interacts with the cytoplasmic loop 2 of SCN5A.

Subcellular Location:
Nucleus. Cytoplasm. Shuttles between the nucleus and cytoplasm.

Tissue Specificity:
Isoform 1 and isoform 2 are ubiquitously expressed.

Similarity:
Belongs to the MOG1 family.

Database links:

Entrez Gene: 29098 Human

Entrez Gene: 57785 Mouse

Entrez Gene: 287419 Rat

Omim: 607954 Human

SwissProt: Q9HD47 Human

SwissProt: Q9JIB0 Mouse

Unigene: 408233 Human

Unigene: 371612 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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