亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
91免费精品国自产拍在线可以看 ,麻豆一区二区在我观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-PLEKHG5/FITC Conjugated antibody (bs-12455R-FITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12455R-FITC
英文名稱 Rabbit Anti-PLEKHG5/FITC Conjugated antibody
中文名稱 FITC標記的凋亡誘導受體PLEKHG5抗體
別    名 PKHG5_HUMAN; Pleckstrin homology domain-containing family G member 5; PH domain-containing family G member 5; Guanine nucleotide exchange factor 720; GEF720.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 染色質和核信號  信號轉導  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 116kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PLEKHG5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a protein that activates the nuclear factor kappa B (NFKB1) signaling pathway. Mutations in this gene are associated with autosomal recessive distal spinal muscular atrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Function:
Guanine nucleotide exchange factor that activates RHOA and maybe the NF-kappa-B signaling pathway. Involved in the control of neuronal cell differentiation. Plays a role in angiogenesis through regulation of endothelial cells chemotaxis.

Subunit:
Interacts with GIPC1/synectin and RHOA.

Subcellular Location:
Cytoplasm. Cytoplasm, perinuclear region. Cell junction. Cell projection, lamellipodium. Note=Predominantly cytoplasmic, however when cells are stimulated found in perinuclear regions. Localized at cell-cell junctions in quiescent endothelial cells, it relocalizes to cytoplasmic vesicle and the leading edge of lamellipodia in migrating endothelial cells.

Tissue Specificity:
Predominantly expressed in the peripheral nervous system and brain. Highest expression is observed in heart, lung, kidney, testis and moderate expression is present in spleen, pancreas, skeletal muscle, ovary and liver. Weakly expressed in glioblastoma (GBM) cell lines.

DISEASE:
Distal spinal muscular atrophy, autosomal recessive, 4 (DSMA4) [MIM:611067]: A neuromuscular disorder. Distal spinal muscular atrophy, also known as distal hereditary motor neuronopathy, represents a heterogeneous group of neuromuscular disorders caused by selective degeneration of motor neurons in the anterior horn of the spinal cord, without sensory deficit in the posterior horn. The overall clinical picture consists of a classical distal muscular atrophy syndrome in the legs without clinical sensory loss. The disease starts with weakness and wasting of distal muscles of the anterior tibial and peroneal compartments of the legs. Later on, weakness and atrophy may expand to the proximal muscles of the lower limbs and/or to the distal upper limbs. DSMA4 is characterized by childhood onset, generalized muscle weakness and atrophy with denervation and normal sensation. Bulbar symptoms and pyramidal signs are absent. Note=The disease is caused by mutations affecting the gene represented in this entry.
Charcot-Marie-Tooth disease, recessive, intermediate type, C (CMTRIC) [MIM:615376]: A form of Charcot-Marie-Tooth disease, a disorder of the peripheral nervous system, characterized by progressive weakness and atrophy, initially of the peroneal muscles and later of the distal muscles of the arms. Recessive intermediate forms of Charcot-Marie-Tooth disease are characterized by clinical and pathologic features intermediate between demyelinating and axonal peripheral neuropathies, and motor median nerve conduction velocities ranging from 25 to 45 m/sec. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain.

Database links:

Entrez Gene: 57449 Human

Entrez Gene: 269608 Mouse

Entrez Gene: 310999 Rat

Omim: 611101 Human

SwissProt: O94827 Human

SwissProt: Q66T02 Mouse

SwissProt: Q6RFZ7 Rat

Unigene: 284232 Human

Unigene: 332102 Mouse

Unigene: 486442 Mouse

Unigene: 20730 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
日韩视频在线精品视频免费观看 | 蜜桃视频极品免费观看 | 欧美亚洲精品中文字幕乱码免费高清 | 久久九九久精品国产综合 | 一区二区三区国模大胆 | 91极品在线观看 | 色噜噜人妻丝袜aV先锋影音先 | 亚洲精品一本之道高清乱码 | 国产福利一区二区三区在线视频 | 粉嫩被两个粗黑疯狂进出 | 校园久久综合激情四射伊人丁香 | 最近高清中文在线字幕在线观看 | 无码区国产区在线播放 | 婷婷六月激情综合一区 | 一级毛片视频免费观看 | 亚洲无吗在线视频 | 亚洲熟女乱色一区二区三区 | 中文字幕亚洲无线码 | 欧美一级久久久久久久久大 | 91福利国产在线播放午夜 | 久久99人妻无码精品一区二区 | 99久久国产综合精品麻豆导演 | 无码人妻精品中文字幕 | 天美传媒TMY0013在线观看 | 丰满白嫩尤物啪啪嗯啊动态图 | 成人AV免费网址在线观看 | 国产精品一区二区AV交换 | 一级A爱做片免费观看国产 成人MV射精无打码视频 | 亚洲AV无码乱码在线观看性色 | 国产真人无码作爱免费视频久 | 日本理伦片午夜理伦片 | 俄罗斯aaaa一级毛片 | 亚洲AV无码成人精品区国产 | 囯精产品一品二品国精91 | 欧美性爱一我在线级片 | 欧美极品护士VIDEOSVIDEO 免费观看一级特黄欧美 | 久久久久久久久66精品片 | 男男H黄动漫啪啪无遮挡网站 | 无码人妻免费一区二区三区 | 一级做a爰片久久毛片免费陪 | 一本一道精品欧美中文字幕 |