亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
18禁无码国内精品久久综合88,国模丽丽啪啪一区二区,午夜精品久久无码av网站
Rabbit Anti-phospho-MAK (Tyr159)/Cy3 Conjugated antibody (bs-18634R-Cy3)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-18634R-Cy3
英文名稱 Rabbit Anti-phospho-MAK (Tyr159)/Cy3 Conjugated antibody
中文名稱 Cy3標(biāo)記的磷酸化絲氨酸/蘇氨酸蛋白激酶MAK抗體
別    名 MAK (phospho Tyr159); MAK (phospho Y159); dJ417M14.2; Mak; MAK_HUMAN; Male germ cell associated kinase; Male germ cell-associated kinase; OTTHUMP00000016025; Rck; Serine/threonine protein kinase MAK; Serine/threonine-protein kinase MAK.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 細(xì)胞生物  發(fā)育生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  激酶和磷酸酶  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Rat,  (predicted: Mouse, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human MAK around the phosphorylation site of Tyr159
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

Function:
Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors (By similarity). Phosphorylates FZR1 in a cell cycle-dependent manner. Plays a role in the transcriptional coactivation of AR. Could play an important function in spermatogenesis.
May play a role in chromosomal stability in prostate cancer cells.

Subcellular Location:
Nucleus. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Midbody. Cell projection > cilium > photoreceptor outer segment. Photoreceptor inner segment. Localized in both the connecting cilia and the outer segment axonemes (By similarity). Localized uniformly in nuclei during interphase, to the mitotic spindle and centrosomes during metaphase and anaphase, and also to midbody at anaphase until telophase.

Tissue Specificity:
Expressed in prostate cancer cell lines at generally higher levels than in normal prostate epithelial cell lines. Isoform 1 is expressed in kidney, testis, lung, trachea, and retina. Isoform 2 is retina-specific where it is expressed in rod and cone photoreceptors.

Post-translational modifications:
Autophosphorylated. Phosphorylated on serine and threonine residues.

DISEASE:
Defects in MAK are the cause of retinitis pigmentosa type 62 (RP62) [MIM:614181]. RP62 is a retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.

Similarity:
Belongs to the protein kinase superfamily.
CMGC Ser/Thr protein kinase family.
CDC2/CDKX subfamily. Contains 1 protein kinase domain.

Database links:

Entrez Gene: 4117 Human

Entrez Gene: 17152 Mouse

Entrez Gene: 25677 Rat

Omim: 154235 Human

SwissProt: P20794 Human

SwissProt: Q04859 Mouse

SwissProt: P20793 Rat

Unigene: 446125 Human

Unigene: 8149 Mouse

Unigene: 9670 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产一级特黄在线播放 | 国产乱女乱子视频在线播放 | 亚洲成AV人片一区二区不卡 | 久久久久亚洲视频 | 亚洲欧美激情精品一区二区 | 性无码免费一区二区三区 | 亚洲日本一线产区和二线产 | 未满十八18禁止免费无码网站 | 日本妇人成熟A片免费观看 亚洲精品永久在线观看 | 久久中文字幕亚洲精品最新 | 精品少妇一区二区三区视频 | 999久久狠狠免费精品 | 精品久久久久久久久久中文字幕 | 激情射精爽到偷偷C视频无码 | 性奴抽插乳中出精没射视频搜索 | 国产无套内射又大又猛又粗又爽 | 国产GAYSEXCHINA男外卖 | 最近的2019中文字幕无吗 | 欧美一级特黄AAAAAAAA片在线看 | 久久精品亚洲精品国产欧美 | 亚洲精品国产精品国自产! 未满十八岁勿入网站WWW | 色涩网站在线观看 | 人妻精品久久久久中文字幕69 | 国产乱人伦偷精品视频免下载 | 给我免费播放片高清在线观看 | 91久久久久久亚洲精品蜜桃 | 国产成人Av大片在线观看 | 文中字幕一区二区三区视频播放 | 一区二区高清无码电影 | 久久人人爽人人爽人人片AV不 | 日本成本人片高清久久免费 | 爱啪网亚洲第一福利网站 | 国产性VIDEOSGRATIS喷潮 | 在线亚洲专区中文字幕 | 好好的曰com久久 | 波多野结衣AV在线播放 | 欧美日韩国产无线码一区 | 久久久久久黃色網站免費 | 国产高清视频免费最新在线 | 国产精品九九久久精品视 | 天堂网资源中文最新版 |