亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
欧美人与拘牲交大全O人禾 ,亚洲色婷婷久久99精品91,国产AV国片精品一区二区
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-NDFIP2/Cy7 Conjugated antibody (bs-19059R-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-19059R-Cy7
英文名稱 Rabbit Anti-NDFIP2/Cy7 Conjugated antibody
中文名稱 Cy7標記的NDFIP2抗體
別    名 Ndfip2; NEDD4 family interacting protein 2; NEDD4 family-interacting protein 2; NEDD4 WW domain binding protein 5A; NEDD4 WW domain-binding protein 5A; NFIP2_HUMAN; Putative MAPK activating protein PM04/PM05/PM06/PM07; Putative MAPK-activating protein PM04/PM05/PM06/PM07; Putative NF kappa B activating protein 413; Putative NF-kappa-B-activating protein 413.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NDFIP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 ∑C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20∑C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ∑C.
產(chǎn)品介紹 background:
NDFIP2 is a 336 amino acid protein that localizes to the membrane of both the endosome and the golgi apparatus. Expressed in kidney, heart, brain, lung, liver, placenta and skeletal muscle, Ndfip2 interacts with NEDD4 and NEDD4-L and is thought to be involved in endocytosis and in the NFⅹB and MAPK signaling pathways. Additionally, Ndfip2 may function as an adaptor protein that may recruit NEDD4 ubiquitin-protein ligases to protein trafficking machinery in the golgi. Ndfip2 is activated by T cells and may be ubiquitinated by NEDD4 or NEDD4-L, an event that does not affect Ndfip2 function. The gene encoding Ndfip2 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.

Function:
Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, may control many cellular processes. Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. May modulate EGFR signaling.

Subunit:
Forms heterodimers with NDFIP1. Interacts with HECT domain-containing E3 ubiquitin-protein ligases, including NEDD4. Interacts with NEDD4L By similarity. Interacts with PTEN. When phosphorylated at Tyr-167, interacts with SRC and LYN SH2 domain. May thus act as a scaffold that recruits SRC to NDFIP1, enhancing NDFIP1 phosphorylation. Interacts with SLC11A2/DMT1. May interact with phosphorylated EGFR.

Subcellular Location:
Endosome membrane. Golgi apparatus membrane. Endosome > multivesicular body membrane.

Tissue Specificity:
Expressed in brain, lung, heart, skeletal muscle, kidney, liver and placenta.

Post-translational modifications:
Ubiquitinated by NEDD4 and ITCH. Also ubiquitinated by NEDD4L. Ubiquitination by NEDD4 or NEDD4L does not affect turnover.
Undergoes transient tyrosine-phosphorylation following EGF stimulation, most probably catalyzed by SRC. Also phosphorylated by LYN and FYN.

Database links:

Entrez Gene: 76273 Mouse

Entrez Gene: 361089 Rat

SwissProt: Q91ZP6 Mouse

SwissProt: F1M5D2 Rat

Unigene: 290669 Mouse

Unigene: 387487 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
最近高清中文字幕无吗免费看 | 久久精品中文字幕第一页国产精品 | 宅男午夜大片又黄又爽大片 | 穿着白丝被强行侵犯漫画 | 国产欧美一区二区精品性色 | 日韩视频高清免费看 | 性一交一乱一伦一色一情孩 | 国产欧美日韩高清在线不卡 | 波多野结衣AV在线播放 | 美女又大又黄www免费网站 | 男同桌上课时狂揉我下面污文 | 波多野结衣av免费观看 | 日韩AV毛片精品久久久 | 人妻体内射精一区二区三四 | av色欲无码人妻中文字幕 | 最新日韩中文字幕 | 欧美人与禽x0x0牲伦交 | 人妻精品内射-AV | 国产成人午夜极速观看 | 精品自拍视频五区六区在线观看 | 欧美精品一区二区蜜臀亚洲 | 欧洲亚洲精品A片久久99果冻 | 最近中文字幕MV免费高清动漫 | 蜜桃臀无码内射一区二区三区 | 中出人妻中文字幕无码 | 校花系列辣h文黑人宫交 | 亚洲一区爱区精品无码 | 韩日美无码精品无码 | 国产午夜精品喷水久久 | 伊人思思久99久女女精品视频 | 中文字幕欧美另类精品亚洲 | 日韩一区二无码专区播放 | 免费看**a一级毛片 国产精品无码AV片在线专区 | 中文精品字幕国产91久久久久久黄无码 | 久久成人永久免费播放 | 中国一级毛片在线观看 | 国产美女裸体无遮挡免费视频高潮 | 国产精品自在线拍国产不卡 | 国产a级三级三级成人国产一级婬片 | 晚上睡不着偷偷看B站 | 伊人久久精品中文字幕 |