亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質(zhì)量反饋  關于我們  聯(lián)系我們
一区二区三区在线观看视频,天天摸夜夜躁躁到高潮av
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-NDFIP2/BF350 Conjugated antibody (bs-19059R-BF350)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-19059R-BF350
英文名稱 Rabbit Anti-NDFIP2/BF350 Conjugated antibody
中文名稱 BF350標記的NDFIP2抗體
別    名 Ndfip2; NEDD4 family interacting protein 2; NEDD4 family-interacting protein 2; NEDD4 WW domain binding protein 5A; NEDD4 WW domain-binding protein 5A; NFIP2_HUMAN; Putative MAPK activating protein PM04/PM05/PM06/PM07; Putative MAPK-activating protein PM04/PM05/PM06/PM07; Putative NF kappa B activating protein 413; Putative NF-kappa-B-activating protein 413.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NDFIP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 ∑C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20∑C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ∑C.
產(chǎn)品介紹 background:
NDFIP2 is a 336 amino acid protein that localizes to the membrane of both the endosome and the golgi apparatus. Expressed in kidney, heart, brain, lung, liver, placenta and skeletal muscle, Ndfip2 interacts with NEDD4 and NEDD4-L and is thought to be involved in endocytosis and in the NFⅹB and MAPK signaling pathways. Additionally, Ndfip2 may function as an adaptor protein that may recruit NEDD4 ubiquitin-protein ligases to protein trafficking machinery in the golgi. Ndfip2 is activated by T cells and may be ubiquitinated by NEDD4 or NEDD4-L, an event that does not affect Ndfip2 function. The gene encoding Ndfip2 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.

Function:
Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, may control many cellular processes. Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. May modulate EGFR signaling.

Subunit:
Forms heterodimers with NDFIP1. Interacts with HECT domain-containing E3 ubiquitin-protein ligases, including NEDD4. Interacts with NEDD4L By similarity. Interacts with PTEN. When phosphorylated at Tyr-167, interacts with SRC and LYN SH2 domain. May thus act as a scaffold that recruits SRC to NDFIP1, enhancing NDFIP1 phosphorylation. Interacts with SLC11A2/DMT1. May interact with phosphorylated EGFR.

Subcellular Location:
Endosome membrane. Golgi apparatus membrane. Endosome > multivesicular body membrane.

Tissue Specificity:
Expressed in brain, lung, heart, skeletal muscle, kidney, liver and placenta.

Post-translational modifications:
Ubiquitinated by NEDD4 and ITCH. Also ubiquitinated by NEDD4L. Ubiquitination by NEDD4 or NEDD4L does not affect turnover.
Undergoes transient tyrosine-phosphorylation following EGF stimulation, most probably catalyzed by SRC. Also phosphorylated by LYN and FYN.

Database links:

Entrez Gene: 76273 Mouse

Entrez Gene: 361089 Rat

SwissProt: Q91ZP6 Mouse

SwissProt: F1M5D2 Rat

Unigene: 290669 Mouse

Unigene: 387487 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
BWBWWBWWW高潮| 国产伦精品一区二区三区在线观看 | 狠狠色综合7777久夜色撩人 | 亚洲国产欧美经典三级 | 欧美午夜精品一区二区蜜桃 | 亚1州区2区3区4区产品图片 | 日本亚洲一区二区三区 | 国产精品国产三级国产AV麻豆 | 久久久久久久国产 | 亚洲成高清三区二区二区中文 | www.91视频.com | 国产精品VA在线播放 | 国内精品久久久久久久小说 | 无码AV熟妇素人内射V在线 | 蜜桃臀无码内射一区二区三区 | 最近日本MV字幕免费观看视频 | chengrenwangzhan免费观看 | 久久精品国产免费观看频道 | 毛av毛aⅴ毛aaa正片 | 亚洲已满18点击进入在线观看 | 亚洲午夜精品无码专区在线播放 | 欧美一级aa系列婷婷99 | 久久久久久久岛国免费观看 | 中文字幕va一区二区三区 | 91精品免费久久久久久久久 | www.xxxx.日本 | 黑白配黑粗硬大疯狂乱叫 | 亚洲中文字幕每日更新 | 高清一区二区三区日本久 | 97超级碰碰碰久久久久总站 | 99视频精品在线 | 三个男人躁我一个爽是什么剧 | 免费又黄又爽1000禁片 | 高潮毛片无遮挡免费高清 | 最火的app排行榜前十名 | 欧美性猛交XXXX乱大交3 | 97精品人妻一区二区三区香蕉 | 亚洲成人电影在线观看精品国产 | 国产特级淫片免费看欧美日韩中文 | 裸露双乳挤奶无遮掩裸体私房视频 | 女儿国3在线观看免费版高清 |