亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
免费伦费一区二区三区四区,国产超碰人人爱被IOS解锁,免费永久在线观看黄网站
Rabbit Anti-TBCE/PE-Cy5 Conjugated antibody (bs-20328R-PE-Cy5)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-20328R-PE-Cy5
英文名稱 Rabbit Anti-TBCE/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標(biāo)記的微管蛋白特定伴侶蛋白E抗體
別    名 HRD; KCS; KCS1; Pac2; tbce; TBCE_HUMAN; Tubulin specific chaperone e; Tubulin-folding cofactor E; Tubulin-specific chaperone E.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  生長(zhǎng)因子和激素  細(xì)胞骨架  細(xì)胞外基質(zhì)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 59kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TBCE
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Microtubules, the primary component of the cytoskeletal network, are highly dynamic structures composed of Alpha/Beta Tubulin heterodimers. Biosynthesis of functional microtubules involve the participation of several chaperones, termed Tubulin folding cofactors A (TBCA), D (TBCD), E (TBCE) and C (TBCC), that act on folding intermediates downstream of the cytosolic chaperon, alternatively named TCP. TBCE (tubulin folding cofactor E), also known as HRD, KCS, KCS1 or pac2, is a 527 amino acid cytoplasmic protein containing one CAP-Gly domain and seven LRR (leucine-rich) repeats. TBCE is involved in the second step of the Tubulin folding pathway and is implicated in the maintenance of the neuronal microtubule network. TBCE associates with microtubules and proteasomes, and protects against misfolded protein stress. Mutations in the gene encoding TBCE are the cause of hypoparathyroidism-retardation-dysmorphism syndrome and Kenny-Caffey syndrome type 1.

Function:
Tubulin-folding protein; involved in the second step of the tubulin folding pathway. Seems to be implicated in the maintenance of the neuronal microtubule network. Involved in regulation of tubulin heterodimer dissociation.

Subunit:
Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state. Cofactors B and E can form a heterodimer which binds to alpha-tubulin and enhances their ability to dissociate tubulin heterodimers.

Subcellular Location:
Cytoplasm (By similarity). Cytoplasm, cytoskeleton (By similarity).

DISEASE:
Defects in TBCE are a cause of hypoparathyroidism-retardation-dysmorphism syndrome (HRD) [MIM:241410]; also known as hypoparathyroidism with short stature, mental retardation, and seizures or Sanjad-Sakati syndrome. HRD is an autosomal recessive disorder reported almost exclusively in Middle Eastern populations.
Defects in TBCE are the cause of Kenny-Caffey syndrome type 1 (KCS1) [MIM:244460]. KCS1 is similar to HRD with the additional features of osteosclerosis and recurrent bacterial infections.

Similarity:
Belongs to the TBCE family. Contains 1 CAP-Gly domain.
Contains 7 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.


Database links:

Entrez Gene: 6905 Human

Entrez Gene: 70430 Mouse

Entrez Gene: 361255 Rat

Omim: 604934 Human

SwissProt: Q15813 Human

SwissProt: Q8CIV8 Mouse

SwissProt: Q5FVQ9 Rat

Unigene: 727621 Human

Unigene: 260209 Mouse

Unigene: 3547 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
√天堂中文www官网 粉嫩METART人体欣赏 | 伊人久久大香线蕉综合 | 欧美最猛性xxxxx亚洲精品 | 无码A∨高潮抽搐流白浆国产 | 中文字幕一区在线观看视频 | 亚洲二区在线视频 | 无码专区—VA亚洲V天堂 | 国产三级日产三级国产AV多人 | 亚洲国产成人精品刺激内射白浆 | 最近高清中文字幕免费MV | 在线免费观看黄色网站 | 免费精品国产自产拍在线观看图片 | 天堂8中文在线最新版官网 91日本在线视频 | 午夜特爽爽爽爽爽爽黄片 | 99久久精品费精品国产一区二区 | 激情动图欧美一区二区 | 亚洲国产精品一区二区三区在线观看 | 蜜桃羞羞小视频在线观看 | 人妻少妇精品视频一区97精品 | 99精品无人区乱码在线观看 | 很黄的爱爱高潮小说的软件 | 日韩丰满少妇无吗视频激情内射 | 最近韩国日本免费高清观看 | 欧美精品九九99久久在观看 | 国产精品国产馆在线真实露脸 | 国产在线观看片免费人成视频 | 亚洲午夜在线播放 | 欧美野性肉体狂欢大派对 | 高清AV熟女一区 | 国产精品手机在线无码援交 | 内射人妻无套中出无码 | 内地级A艳片高清免费播放 国产精品无码不卡系列在线 | 老色皮永久免费网站 | 欧美日韩免费在线 | 欧美透明丰满内衣内裤 | 日本熟妇丰满XXXXX18 | 精品极品三大极久久久久 | 欧美乱色伦图片区小说 | 久久精品九九亚洲精品 | 亚洲第一天堂WWW网站 | 污污内射一区二区三区 |