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Rabbit Anti-NRIP1/BF488 Conjugated antibody (bs-8739R-BF488)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-8739R-BF488
英文名稱(chēng) Rabbit Anti-NRIP1/BF488 Conjugated antibody
中文名稱(chēng) BF488標(biāo)記的核受體相互作用蛋白1抗體
別    名 NRIP 1; NRIP1; NRIP1_HUMAN; Nuclear factor RIP 140; Nuclear factor RIP140; Nuclear receptor interacting protein 1; Nuclear receptor-interacting protein 1; Receptor interacting protein 140; Receptor-interacting protein 140; RIP 140; RIP140.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 140kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NRIP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 Function:
Modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1. Also modulates transcriptional repression by nuclear hormone receptors.

Subcellular Location:
Nucleus. Localized to discrete foci and redistributes to larger nuclear domains upon binding to ligand-bound NR3C1.

Post-translational modifications:
Acetylation regulates its nuclear translocation and corepressive activity (By similarity). Acetylation abolishes interaction with CTBP1. Phosphorylation enhances interaction with YWHAH.

Database links:

Entrez Gene: 524960 Cow

Entrez Gene: 478385 Dog

Entrez Gene: 8204 Human

Entrez Gene: 268903 Mouse

Entrez Gene: 304157 Rat

Omim: 602490 Human

SwissProt: P48552 Human

SwissProt: Q8CBD1 Mouse

Unigene: 155017 Human

Unigene: 455873 Mouse

Unigene: 74711 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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