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Rabbit Anti-NUPL1/Gold Conjugated antibody (bs-19569R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-19569R-Gold
英文名稱 Rabbit Anti-NUPL1/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的核孔蛋白樣蛋白1抗體
別    名 KIAA0410; Nucleoporin like 1; Nucleoporin p58/p45; NUPL 1; OTTHUMP00000018146; OTTHUMP00000042323; PRO2463.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 染色質(zhì)和核信號  信號轉(zhuǎn)導(dǎo)  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, Chicken, Dog, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 61kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NUPL1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Function:
Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.

Subunit:
Component of the p62 complex, a complex at least composed of NUP62, NUP54, and NUPL1. Interacts with NUTF2. Interacts with SRP1-alpha and Importin p97 proteins when they are together, but not with SRP1-alpha protein alone (By similarity).

Subcellular Location:
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note: Biased towards cytoplasmic side. Central region of the nuclear pore complex, within the transporter.

Database links:

Entrez Gene: 9818 Human

Entrez Gene: 71844 Mouse

Entrez Gene: 245922 Rat

Omim: 607615 Human

SwissProt: Q9BVL2 Human

SwissProt: Q8R332 Mouse

SwissProt: P70581 Rat

Unigene: 507537 Human

Unigene: 258051 Mouse

Unigene: 11099 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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