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Rabbit Anti-Rhophilin 2/APC Conjugated antibody (bs-19878R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19878R-APC
英文名稱 Rabbit Anti-Rhophilin 2/APC Conjugated antibody
中文名稱 APC標記的Rho結合蛋白2抗體
別    名 76 kDa RhoB effector protein; D7Ertd784e; GTP Rho binding protein 2; GTP-Rho-binding protein 2; p76RBE; Rho GTPase binding protein 2; RhoB effector; RhoBP; Rhophilin 2; Rhophilin; Rhophilin like protein; Rhophilin like Rho GTPase binding protein; Rhophilin Rho GTPase binding protein 2; Rhophilin-2; Rhophilin2; RHPN 2; RHPN2; RHPN2_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 77kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Rhophilin 2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq, Apr 2009]

Function:
Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity.

Subunit:
Interacts with GTP-bound RhoA and RhoB.

Subcellular Location:
Cytoplasm > perinuclear region.

Tissue Specificity:
Widely expressed. Highly expressed in prostate, trachea, stomach, colon, thyroid and pancreas. Expressed at lower level in brain, spinal cord, kidney, placenta and liver.

Similarity:
Belongs to the RHPN family.
Contains 1 BRO1 domain.
Contains 1 PDZ (DHR) domain.
Contains 1 REM (Hr1) repeat.

Database links:

Entrez Gene: 533687 Cow

Entrez Gene: 85415 Human

Entrez Gene: 52428 Mouse

Entrez Gene: 308516 Rat

SwissProt: A4FUC9 Cow

SwissProt: Q8IUC4 Human

SwissProt: Q8BWR8 Mouse

Unigene: 466435 Human

Unigene: 286600 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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