亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产精品 久久久精品软件下载,无码精品最新在线观看2020
Rabbit Anti-phospho-Smad1 (Ser187) /Cy5 Conjugated antibody (bs-19917R-Cy5)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-19917R-Cy5
英文名稱 Rabbit Anti-phospho-Smad1 (Ser187) /Cy5 Conjugated antibody
中文名稱 Cy5標(biāo)記的磷酸化細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)分子Smad-1抗體
別    名 Smad1 (phospho S187); p-Smad1 (phospho S187); BSP 1; BSP-1; BSP1; Dwarfin A; DwfA; hSMAD 1; hSMAD1; JV 41; JV4 1; JV4-1; JV41; MAD homolog 1; MAD mothers against decapentaplegic homolog 1; Mad related protein 1; Mad-related protein 1; MADH 1; MADH1; Madr 1; MADR1; Mothers against decapentaplegic homolog 1; Mothers against DPP homolog 1; Sma and Mad related protein 1; SMA- AND MAD-RELATED PROTEIN 1; SMAD 1; SMAD family member 1; SMAD mothers against DPP homolog 1; SMAD mothers against DPP homolog 1 Drosophila; Smad1; Smad1; SMAD1_HUMAN; Spinal muscular atrophy distal with upper limb predominance; TGF beta signaling protein 1; Transforming growth factor beta signaling protein 1; Transforming growth factor-beta-signaling protein 1.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  細(xì)胞生物  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Chicken, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human Smad1 around the phosphorylation site of Ser187.
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

Function:
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).
SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.

Subcellular Location:
Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4. Co-localizes with LEMD3 at the nucleus inner membrane.

Tissue Specificity:
Ubiquitous. Highest expression seen in the heart and skeletal muscle.

Post-translational modifications:
Phosphorylated on serine by BMP type 1 receptor kinase.
Ubiquitin-mediated proteolysis by SMAD-specific E3 ubiquitin ligase SMURF1.

Similarity:
Belongs to the dwarfin/SMAD family.
Contains 1 MH1 (MAD homology 1) domain.
Contains 1 MH2 (MAD homology 2) domain.

Database links:

Entrez Gene: 4086 Human

Entrez Gene: 17125 Mouse

Omim: 601595 Human

SwissProt: Q15797 Human

SwissProt: P70340 Mouse

Unigene: 604588 Human

Unigene: 223717 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
日韩欧美国产丝袜大香蕉 | 人妻少妇精品视频一区97精品 | 精品国产乱码久久久久久软件大全 | 欧美午夜精选久久久A | 中国女人一级毛片 | 最近2018中文字幕在线高清第一页 | 国产一级a毛一级a看免费视频 | 少妇真人直播APP | 一二三四视频免费社区5 | 在线视频精品免费 | 国产乱熟肥女视频网站 | 日本老妇一级特黄aa大片 | 久久午夜夜伦鲁鲁片不卡 | 国产AAA片精品网站 打扑克污黄对网站在线看 男女激情射精国产精品久久 | 成熟少妇大片免费看 | 内射豹纹少妇-V11AV | 内射人妻精品丨色AV无码 | 亚洲午夜精品无码专区在线播放 | 中文字幕亚洲一区 | 在线永久看片免费的视频 | 国产欧美一区二区三区视频 | 国产精品久久一区二区三蜜桃 | 97国产大学生情侣酒店 | 久久综合色天天久久综合图片 | 亚洲色欲AV无码成人专区 | 日本一级A片在线观看播放 久久精品中文字幕第一页国产精品 | 真人与拘做受免费视频 | 免费麻豆国产黄网站在线观看 | 日韩特黄特色大片免费视频 | 草莓黄瓜蜜桃视频app下载 | 国产伦精品一区二区三区精品 | 欧美成人久久一级c片免费 免费视频国产在线观看 | 亚洲地址一地址二地址三 | 久久久橹橹橹久久久久高清 | 狠狠色丁香久久婷婷综合_中 | 少妇内射高潮福利炮 | 奶头好大揉着好爽gif动态 | 日韩成人在线视频 | 国产精品日本不卡一区二区 | 肉到痉挛中出痴汉在线播放 | AV无码久久久久不卡网站毛片 |