亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日韩中文字幕免费的视频在线看网站 ,免费无码精品黄AV电影
Rabbit Anti-phospho-Smad1 (Ser187) /APC Conjugated antibody (bs-19917R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-19917R-APC
英文名稱 Rabbit Anti-phospho-Smad1 (Ser187) /APC Conjugated antibody
中文名稱 APC標(biāo)記的磷酸化細(xì)胞信號轉(zhuǎn)導(dǎo)分子Smad-1抗體
別    名 Smad1 (phospho S187); p-Smad1 (phospho S187); BSP 1; BSP-1; BSP1; Dwarfin A; DwfA; hSMAD 1; hSMAD1; JV 41; JV4 1; JV4-1; JV41; MAD homolog 1; MAD mothers against decapentaplegic homolog 1; Mad related protein 1; Mad-related protein 1; MADH 1; MADH1; Madr 1; MADR1; Mothers against decapentaplegic homolog 1; Mothers against DPP homolog 1; Sma and Mad related protein 1; SMA- AND MAD-RELATED PROTEIN 1; SMAD 1; SMAD family member 1; SMAD mothers against DPP homolog 1; SMAD mothers against DPP homolog 1 Drosophila; Smad1; Smad1; SMAD1_HUMAN; Spinal muscular atrophy distal with upper limb predominance; TGF beta signaling protein 1; Transforming growth factor beta signaling protein 1; Transforming growth factor-beta-signaling protein 1.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  細(xì)胞生物  染色質(zhì)和核信號  信號轉(zhuǎn)導(dǎo)  干細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Chicken, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human Smad1 around the phosphorylation site of Ser187.
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

Function:
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).
SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.

Subcellular Location:
Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4. Co-localizes with LEMD3 at the nucleus inner membrane.

Tissue Specificity:
Ubiquitous. Highest expression seen in the heart and skeletal muscle.

Post-translational modifications:
Phosphorylated on serine by BMP type 1 receptor kinase.
Ubiquitin-mediated proteolysis by SMAD-specific E3 ubiquitin ligase SMURF1.

Similarity:
Belongs to the dwarfin/SMAD family.
Contains 1 MH1 (MAD homology 1) domain.
Contains 1 MH2 (MAD homology 2) domain.

Database links:

Entrez Gene: 4086 Human

Entrez Gene: 17125 Mouse

Omim: 601595 Human

SwissProt: Q15797 Human

SwissProt: P70340 Mouse

Unigene: 604588 Human

Unigene: 223717 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
一级av一片久久免费观看 | 国内精品久久久久久网站 | 色欲久久久久久综合网精品 | 国产精品手机在线无码援交 | 国产超碰AV人人做人人爽 | 久久国产精品偷任你爽任你A | 久久亚洲AV无码精品福利 | 狠狠色色综合网站 | 国产伦精品一区二区免费 | 国产乱妇乱子视频在线播放国产 | 亚洲一区二区三区高清网 | 国产美女视频免费观看的网站 | 国产乱老熟视频乱老熟女51 | 毛片TV网站无套内射TV网站 | 久久人人做人人爽久久99国产乱子伦精品免 | 2021亚洲无码视频 | 荡公乱妇蒂芙尼中文字幕 | 国内精品一级毛片免费看 | 兔费看少妇性L交大片免费 亚洲AV√最新天堂版资源地址在线官网 | 特级做a爰片毛片免费看 | 女的被弄到高潮娇喘喷水视频 | 国产大片在线播放 | 日欧片内射AV影院频道 | 狂处让老二爽18p | 任我鲁精品视频精品 | 午夜三级a三级三点窝558888 | 最火的app排行榜前十名 | 国产精品亚洲专区在线播放 | 日韩一区二区三区视频在线观看 | 亚洲午夜成激人情在线影院 | 亚洲日韩精品一区二区二 | 日韩精品亚洲一区二区三区 | 日出水了特别黄的视频 | 久久久无码精品一区二区三区 | 久久精品国产9久久综合 | 欧美成人精品欧美一级乱黄 | 亚洲老妈激情一区二区三区 | 精品免费囯产一区二区三区四区 | 亚洲爆乳无码精品AAA片蜜桃 | 久久97精品久久久久久久看片 | 久久久久亚洲女同一区二区 |