亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
97人人超碰国产精品最新,精品亚洲A∨无码一区二区三区
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-Smad1 (Ser187) /PE-Cy7 Conjugated antibody (bs-19917R-PE-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19917R-PE-Cy7
英文名稱 Rabbit Anti-phospho-Smad1 (Ser187) /PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標記的磷酸化細胞信號轉導分子Smad-1抗體
別    名 Smad1 (phospho S187); p-Smad1 (phospho S187); BSP 1; BSP-1; BSP1; Dwarfin A; DwfA; hSMAD 1; hSMAD1; JV 41; JV4 1; JV4-1; JV41; MAD homolog 1; MAD mothers against decapentaplegic homolog 1; Mad related protein 1; Mad-related protein 1; MADH 1; MADH1; Madr 1; MADR1; Mothers against decapentaplegic homolog 1; Mothers against DPP homolog 1; Sma and Mad related protein 1; SMA- AND MAD-RELATED PROTEIN 1; SMAD 1; SMAD family member 1; SMAD mothers against DPP homolog 1; SMAD mothers against DPP homolog 1 Drosophila; Smad1; Smad1; SMAD1_HUMAN; Spinal muscular atrophy distal with upper limb predominance; TGF beta signaling protein 1; Transforming growth factor beta signaling protein 1; Transforming growth factor-beta-signaling protein 1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 腫瘤  細胞生物  染色質和核信號  信號轉導  干細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Chicken, Pig, Cow, Horse, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human Smad1 around the phosphorylation site of Ser187.
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

Function:
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).
SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.

Subcellular Location:
Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4. Co-localizes with LEMD3 at the nucleus inner membrane.

Tissue Specificity:
Ubiquitous. Highest expression seen in the heart and skeletal muscle.

Post-translational modifications:
Phosphorylated on serine by BMP type 1 receptor kinase.
Ubiquitin-mediated proteolysis by SMAD-specific E3 ubiquitin ligase SMURF1.

Similarity:
Belongs to the dwarfin/SMAD family.
Contains 1 MH1 (MAD homology 1) domain.
Contains 1 MH2 (MAD homology 2) domain.

Database links:

Entrez Gene: 4086 Human

Entrez Gene: 17125 Mouse

Omim: 601595 Human

SwissProt: Q15797 Human

SwissProt: P70340 Mouse

Unigene: 604588 Human

Unigene: 223717 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
亚洲日本香蕉视频观看视频 | 国产欧美日韩亚洲精品区 | 亚洲调教自慰喷水AV无码 | 99国产亚洲精品无码成人69V | 久久99久国产精品黄毛片 | WWW成人国产高清内射 | 精品久久久久久无码不卡 | 91精品久久久久久久99蜜桃91 | 欧美透明丰满内衣内裤 | 狂躁美女大BBBBBB视频1 | 免费观看成人久久网免费观看 | 夜晚成人18禁区导航网站 | 日韩熟妇啪啪无码视频 | 欧日韩无套内射变态 | 视频一区在线免费观看 | 女性高爱潮AAAA级视频免费 | 精品亚洲一区二区三区在线观看 | 人妻少妇久久中文字幕app | 麻豆亚洲精品中文字幕一麻豆 | 午夜亚洲国产理论片一二三四 | 伊人久久大香线蕉AV一区二 | 屁屁国产第1页草草影院 | 精品亚洲一区二区在线播放 | 日韩丰满少妇无吗视频激情内射 | 中文字幕久久精品无码综合网 | 精品国产粉嫩内射白浆内射双马尾 | 欧美性爱视频免费观看 | 男女一级毛片免费视频看 | 免费的很污的很黄的网站 | 亚洲精品123区在线观看 | 97人妻精品专区久久久久 | 婷婷色婷婷开心五月四房播播久久 | 成年在线观看免费高清完整版视频 | 日韩一级精品久久久久 | 无码人妻精品一区二区三区千菊 | 国产黄A三级三级三级看三级 | 成人午夜精品网站在线观看 | 久久综合经典国产二区无码 | 在线观看黄网视频免费播放 | 欧洲性开放大片免费观看视频 | 国产精品你当然比游戏重要 |