亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日本动态120秒免费,91普通话国产对白在线
Rabbit Anti-PACE4/Gold Conjugated antibody (bs-19997R-Gold)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-19997R-Gold
英文名稱(chēng) Rabbit Anti-PACE4/Gold Conjugated antibody
中文名稱(chēng) 膠體金標(biāo)記的PACE4蛋白抗體
別    名 Paired basic amino acid cleaving enzyme 4; paired basic amino acid cleaving system 4; PCSK6; PCSK6_HUMAN; Proprotein convertase subtilisin/kexin type 6; SPC4; Subtilisin like protease; Subtilisin-like proprotein convertase 4; subtilisin/kexin like protease PACE4; Subtilisin/kexin-like protease PACE4.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  泛素  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 91kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PACE4
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. The encoded protease is constitutively secreted into the extracellular matrix and expressed in many tissues, including neuroendocrine, liver, gut, and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression and left-right patterning. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2014]

Function:
Likely to represent an endoprotease activity within the constitutive secretory pathway, with unique restricted distribution in both neuroendocrine and non-neuroendocrine tissues and capable of cleavage at the RX(K/R)R consensus motif.

Subcellular Location:
Secreted; Endomembrane system. Retained intracellularly probably through a hydrophobic cluster in their C-terminus and Endoplasmic reticulum. Not secreted, remains probably in zymogen form in endoplasmic reticulum.

Tissue Specificity:
Each PACE4 isoform exhibits a unique restricted distribution. Isoform PACE4A-I is expressed in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, but at comparatively higher levels in the liver. Isoform PACE4A-II is at least expressed in placenta. Isoform PACE4B was only found in the embryonic kidney cell line from which it was isolated. Isoform PACE4C and isoform PACE4D are expressed in placenta. Isoform PACE4E-I is expressed in cerebellum, placenta and pituitary. Isoform PACE4E-II is at least present in cerebellum.

Post-translational modifications:
The PACE4A-I precursor protein seems to exist in the reticulum endoplasmic as both a monomer and a dimer-sized complex whereas mature PACE4A-I exists only as a monomer, suggesting that propeptide cleavage affects its tertiary or quaternary structure.

Similarity:
Belongs to the peptidase S8 family.
Contains 1 homo B/P domain.
Contains 1 PLAC domain.

Database links:

Entrez Gene: 524684 Cow

Entrez Gene: 488703 Dog

Entrez Gene: 100673009 Elephant

Entrez Gene: 100057677 Horse

Entrez Gene: 5046 Human

Entrez Gene: 100405129 Marmoset (common)

Entrez Gene: 18553 Mouse

Entrez Gene: 100020955 Opossum

Entrez Gene: 100152144 Pig

Entrez Gene: 25507 Rat

Omim: 167405 Human

SwissProt: P29122 Human

SwissProt: Q63415 Rat

Unigene: 498494 Human

Unigene: 665989 Human

Unigene: 950 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
精品国产午夜福利在线观看 | 宝贝乖调教跪趴SM主人玩具HH | 肉到痉挛中出痴汉在线播放 | 亚欧成人毛片一区二区三区四区 | 久久经典免费视频 | 少妇无码太爽了视频在线播放 | 中文字幕一区中文亚洲 | 午夜亚洲国产理论片一二三四 | 亚洲精品嫩草研究院久久 | 亚洲精品成a人在线观看 | 欧美成人免费高清二区三区 | 洗澡被公强奷30分钟在线观看 | 久久久久精品国产亚洲av麻豆 | 国产www在线观看 | 一本—道久久a久久精品蜜桃 | 中文字幕 日韩 国产 | 国产爱豆果冻传媒在线观看 | 亚洲精品不卡午夜精品 | 久久久久久国产a免费观看黄色大片 | 国产精品一区二区尿失禁 | 久久夜色邦福利网 | 无码精品A∨在线观看中文 欧美激情视频在线观看一区二区三区 | 国产精品性做久久久久久 | 国产高潮国产高潮久久久无码 | 国产精品伦一区二区三级视频 | 99re久久在热线播放最新地址 | 小短文H啪纯肉公交车 | 亚欧日韩毛片在线看免费网站 | 男女激情无遮挡免费视频 | 国产免费人成视频网站在线18 | 97久精品国产片一区二区三区 | 日韩一区二区视频在线观看 | 日韩欧美一区二区三区久久婷婷 | 一本久久综合亚洲鲁鲁五月天 | 男男被一根又一根H强迫NP | 欧美精品九九99久久在免费线 | 国产全肉乱妇杂乱视频 | 国产成人Av大片在线观看 | 国产精品日韩欧美一区二区三区 | 久久精品成人91一区二区孕妇 | 国产AV无码专区亚洲A∨毛片 |