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Rabbit Anti-PP11/Gold Conjugated antibody (bs-21050R-Gold)
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說(shuō) 明 書(shū): 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-21050R-Gold
英文名稱 Rabbit Anti-PP11/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的胎盤(pán)蛋白11抗體
別    名 22 serine protease; 26 serine protease; Endonuclease, polyU-specific; endou; ENDOU_HUMAN; P11; Placental protein 11; Poly(U)-specific endoribonuclease; PP11; Pp11r; Protein endoU; PRSS26; Uridylate-specific endoribonuclease.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  發(fā)育生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  表觀遺傳學(xué)  泛素  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PP11
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene encodes a protein with protease activity and is expressed in the placenta. The protein may be useful as a tumor marker. Multiple alternatively spliced transcript variants have been found for this protein. [provided by RefSeq, Feb 2010]

Function:
Endoribonuclease that cleaves single-stranded RNAs at uridylates and releases products that have 2'-3'-cyclic phosphate termini.

Subcellular Location:
Secreted.

Tissue Specificity:
Placental-specific, but also associated with various malignant neoplasms.

Post-translational modifications:
It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.

Similarity:
Belongs to the ENDOU family.
Contains 2 SMB (somatomedin-B) domains.

Database links:

Entrez Gene: 525399 Cow

Entrez Gene: 8909 Human

Entrez Gene: 19011 Mouse

Entrez Gene: 680317 Rat

Omim: 606720 Human

SwissProt: A6QLQ8 Cow

SwissProt: P21128 Human

SwissProt: Q3V188 Mouse

Unigene: 997 Human

Unigene: 1001 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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