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Rabbit Anti-PP11/AP Conjugated antibody (bs-21050R-AP)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-21050R-AP
英文名稱 Rabbit Anti-PP11/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的胎盤蛋白11抗體
別    名 22 serine protease; 26 serine protease; Endonuclease, polyU-specific; endou; ENDOU_HUMAN; P11; Placental protein 11; Poly(U)-specific endoribonuclease; PP11; Pp11r; Protein endoU; PRSS26; Uridylate-specific endoribonuclease.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  發(fā)育生物學  信號轉導  表觀遺傳學  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產(chǎn)品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PP11
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a protein with protease activity and is expressed in the placenta. The protein may be useful as a tumor marker. Multiple alternatively spliced transcript variants have been found for this protein. [provided by RefSeq, Feb 2010]

Function:
Endoribonuclease that cleaves single-stranded RNAs at uridylates and releases products that have 2'-3'-cyclic phosphate termini.

Subcellular Location:
Secreted.

Tissue Specificity:
Placental-specific, but also associated with various malignant neoplasms.

Post-translational modifications:
It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.

Similarity:
Belongs to the ENDOU family.
Contains 2 SMB (somatomedin-B) domains.

Database links:

Entrez Gene: 525399 Cow

Entrez Gene: 8909 Human

Entrez Gene: 19011 Mouse

Entrez Gene: 680317 Rat

Omim: 606720 Human

SwissProt: A6QLQ8 Cow

SwissProt: P21128 Human

SwissProt: Q3V188 Mouse

Unigene: 997 Human

Unigene: 1001 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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