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Rabbit Anti-GRINA/BF488 Conjugated antibody (bs-20059R-BF488)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-20059R-BF488
英文名稱 Rabbit Anti-GRINA/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的谷氨酸受體相關(guān)蛋白1抗體
別    名 Glutamate [NMDA] receptor associated protein 1; Glutamate receptor, ionotropic, N methyl D aspartate associated protein 1 (glutamate binding); Glutamate receptor, NMDA subtype, glutamate binding subunit; HNRGW; LFG1; MGC99687; NMDA receptor glutamate binding subunit; NMDARA1; Putative MAPK activating protein PM02; TMBIM3; Transmembrane BAX inhibitor motif containing 3; LFG1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 神經(jīng)生物學(xué)  通道蛋白  細(xì)胞膜受體  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Cow, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GRINA
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, CREB function and gene regulation. As one of the four major proteins of the NMDA receptor ion channel, GRINA (Glutamate [NMDA] receptor-associated protein 1), also designated NMDA receptor glutamate-binding subunit or putative MAPK-activating protein PM02, is a 371 amino acid multi-pass transmembrane protein. Due to the chromosomal location of the gene encoding GRINA, studies have linked possible GRINA involvement with a form of idiopathic generalized epilepsy.

Function:
Potential apoptotic regulator.

Subcellular Location:
Membrane; Multi-pass membrane protein (potential).

Similarity:
Belongs to the BI1 family. LFG subfamily.

Database links:

Entrez Gene: 2907 Human

Omim: 138251 Human

SwissProt: Q7Z429 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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