亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
99RE久久精品国产,国产一卡 二卡三卡四卡无卡乱码视频
Rabbit Anti-RASGRP4/Cy5 Conjugated antibody (bs-19731R-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-19731R-Cy5
英文名稱 Rabbit Anti-RASGRP4/Cy5 Conjugated antibody
中文名稱 Cy5標(biāo)記的Ras蛋白特異鳥嘌呤核苷酸釋放因子4抗體
別    名 RASGRP-4; GRP4_HUMAN; Guanyl nucleotide releasing protein 4; RAS guanyl releasing protein 4; RAS guanyl-releasing protein 4; RASGRP 4.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Dog, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 75kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RASGRP4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors. It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands. This protein was shown to activate H-Ras in a cation-dependent manner in vitro. Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways. Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]

Function:
Functions as a cation- and diacylglycerol (DAG)-regulated nucleotide exchange factor activating Ras through the exchange of bound GDP for GTP. May function in mast cells differentiation.

Subcellular Location:
Cytoplasm. Cell membrane. Recruited to membranes upon activation by DAG.

Tissue Specificity:
Expressed by mast cells and their progenitors (at protein level). Specifically expressed in mononuclear leukocytes. Highly expressed in myeloid cells compared to lymphoid cells. Also detected in heart, skeletal muscle, spleen, liver, placenta and lung. Not detected in brain. Isoform 1 is the major isoform in normal individuals. Isoform 2 is more significantly expressed in a patient with asthma. Isoform 3 is more significantly expressed in a patient with asthma and a mastocytosis patient.

Similarity:
Belongs to the RASGRP family.
Contains 1 EF-hand domain.
Contains 1 N-terminal Ras-GEF domain.
Contains 1 phorbol-ester/DAG-type zinc finger.
Contains 1 Ras-GEF domain.

Database links:

Entrez Gene: 115727 Human

Entrez Gene: 233046 Mouse

Entrez Gene: 170668 Rat

Omim: 607320 Human

SwissProt: Q8TDF6 Human

SwissProt: Q8BTM9 Mouse

SwissProt: Q8R5I4 Rat

Unigene: 130434 Human

Unigene: 465324 Mouse

Unigene: 213071 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
久爱成欢视频在线观看 | miaa213永濑唯在线观看 | 内射白嫩少妇超碰 | 国产在线观看www | 久99久精品视频免费观看v | 久久久久久精品免费自慰 | 40岁成熟女人牲交片 | 伊人久久无码av一区二区三区 | 亚洲AV日韩AV无码AV一区二区三区 | 亚洲AV无码乱码国产麻豆穿越 | 97夜夜澡人人爽人人喊中国片 | 韩国美女丝袜一区二区 | 国产日韩精品一区二区三区在线 | 国产精品亚洲综合五月天 | 黄桃AV无码免费一区二区三区 | 学生被强奷到高潮喷水在线观看 | 国产手机在线国内精品 | 国产日韩精品一区二区在线观看 | 116美女写真成人午夜视频 | 国产黄A真人一级无码毛片一区二区三区 | 国产精品手机在线无码援交 | 日韩免费一区二区三区在线 | 国产精品网站在线观看免费传媒 | 女人18片毛片60分钟 | 久久91久久91精品免费观看 | 91精品国产综合久久久久久 | 中文字幕国产精品高潮呻吟久久av无码 | 久久久久Av免费无码久久 | 国内精品久久久久久久999下 | 桶机120秒桶机免费网站大全 | 亚洲精品国产精品国自产! 未满十八岁勿入网站WWW | 国产亚洲精品无码AA在线观看 | 久久久久久久国产免费看 | 性欧美18处19处破在线观看 | 国产精品丰满无码理论片 | 正在播放羽月希与黑人bd在线 | 久久无码精品一区二区三区 | 欧美成人精品第一区二区三区 | 男女免费观看在线爽爽爽视频 | 韩国美女精品久久久久久久 | 最近日本字幕MV高清在线观看 |