亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
欧美白嫩精品一区二区,毛片在线观看地址
Rabbit Anti-RASGRP4/PE-Cy5.5 Conjugated antibody (bs-19731R-PE-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-19731R-PE-Cy5.5
英文名稱 Rabbit Anti-RASGRP4/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標(biāo)記的Ras蛋白特異鳥嘌呤核苷酸釋放因子4抗體
別    名 RASGRP-4; GRP4_HUMAN; Guanyl nucleotide releasing protein 4; RAS guanyl releasing protein 4; RAS guanyl-releasing protein 4; RASGRP 4.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Dog, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 75kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RASGRP4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors. It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands. This protein was shown to activate H-Ras in a cation-dependent manner in vitro. Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways. Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]

Function:
Functions as a cation- and diacylglycerol (DAG)-regulated nucleotide exchange factor activating Ras through the exchange of bound GDP for GTP. May function in mast cells differentiation.

Subcellular Location:
Cytoplasm. Cell membrane. Recruited to membranes upon activation by DAG.

Tissue Specificity:
Expressed by mast cells and their progenitors (at protein level). Specifically expressed in mononuclear leukocytes. Highly expressed in myeloid cells compared to lymphoid cells. Also detected in heart, skeletal muscle, spleen, liver, placenta and lung. Not detected in brain. Isoform 1 is the major isoform in normal individuals. Isoform 2 is more significantly expressed in a patient with asthma. Isoform 3 is more significantly expressed in a patient with asthma and a mastocytosis patient.

Similarity:
Belongs to the RASGRP family.
Contains 1 EF-hand domain.
Contains 1 N-terminal Ras-GEF domain.
Contains 1 phorbol-ester/DAG-type zinc finger.
Contains 1 Ras-GEF domain.

Database links:

Entrez Gene: 115727 Human

Entrez Gene: 233046 Mouse

Entrez Gene: 170668 Rat

Omim: 607320 Human

SwissProt: Q8TDF6 Human

SwissProt: Q8BTM9 Mouse

SwissProt: Q8R5I4 Rat

Unigene: 130434 Human

Unigene: 465324 Mouse

Unigene: 213071 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
久久夜色精品国产噜噜亚洲av | 欧美精品综合视频一区二区 | 国产精品久久久久精品 | 国产精品免费一区二区区 | 亚洲乱码日产精品BD在线看 | 国产第一页浮力影院草草 | 亚洲欧美日韩一区二区在线观看 | 亚洲精品无码不卡在线播HE | 国产人成一区二区三区影院 | 特级做a爰片毛片免费看 | 久久91精品国产91久久户 | 久久国产精品99精品国产 | **女人一级毛片免费视频观看 | 少妇内射兰兰久久 | 亚洲中文字幕在线乱妇 | 一级a性色生活片久久无码火 | 永久免费看啪啪网址入口 | 两根大肉大捧一进一出好爽视频 | 成人欧美一区二区三区白人 | 55大东北熟女啪啪嗷嗷叫 | 精品日产1区2卡三卡麻豆 | 欧美日韩成人VA精品一区二区三区不卡 | 久久99久久66精品99久久综合 | 一区二区三区四区在线观看视频 | 中文字幕亚洲第一 | 嫩BBB槡BBBB槡BBBB | 日韩精品一区二区三区免费视频 | 日韩欧美中文字幕公布 | 在线观看免费av网站 | 国产高清国内精品福利色噜噜 | 精品一区二区三区高清免费观看 | 男女无套内射白将在线线国语 | 精品无码一区二区三区亚洲桃色 | 人妻妺妺窝人体色WWW聚色窝 | 66亚洲一卡2卡新区成片发布 | 在线观看日本污污ww网站 | 丰满少妇女人A毛片视频 | XXX2高清在线观看免费视频 | 日本三级带日本三级带黄国产 | 亚洲日韩AV一级午夜在线 | 国产在线视频欧美一区二区三区 |