亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
AV毛片无码乱码国产精品,91麻豆精品激情在线观看最新
Rabbit Anti-DEF6/IBP/Biotin Conjugated antibody (bs-20306R-Bio)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-20306R-Bio
英文名稱 Rabbit Anti-DEF6/IBP/Biotin Conjugated antibody
中文名稱 生物素標(biāo)記的干擾素調(diào)節(jié)因子4結(jié)合蛋白抗體
別    名 DEF-6; Def6; DEFI6_HUMAN; Differentially expressed in FDCP 6 homolog; Differentially expressed in FDCP 6 homologue mouse; IBP; IRF4-binding protein; Swap70 like adapter of T cells.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, Rabbit, )
產(chǎn)品應(yīng)用 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 74kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DEF6/IBP
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
DEF6 is a 631 amino acid protein that is widely expressed in T and B cells of the immune system. Localized to the nucleus, cytoplasm and cell membrane, DEF6 is a phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) that functions to activate Rho GTPases such as Rac 1, Cdc42 and Rho A. Via its ability to activate various Rho GTPases, DEF6 can regulate cell shape, movement and polarity and, through its interaction with T helper cells, DEF6 can also help mediate the immune response. DEF6 contains one PH (pleckstrin homology) domain which is required for binding to phosphatidylinositol 3,4,5-trisphosphate and subsequent recruitment to the plasma membrane.

Function:
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP-70 signaling.

Subunit:
Interacts with ZAP70 (By similarity). Interacts with IRF4, activated RAC1 and F-actin. Both the phosphorylated and non-phosphorylated forms bind phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3).

Subcellular Location:
Cytoplasm. Cell membrane. Nucleus. Recruited to the plasma membrane upon binding phosphatidylinositol 3,4,5-trisphosphate.

Tissue Specificity:
Broadly expressed in the immune system and can be detected in T and B-cells.

Post-translational modifications:
Tyrosine-phosphorylated by tyrosine-protein kinase LCK in response to T-cell activation.

Similarity:
Contains 1 PH domain.

Database links:

Entrez Gene: 50619 Human

Entrez Gene: 23853 Mouse

Entrez Gene: 309642 Rat

Omim: 610094 Human

SwissProt: Q9H4E7 Human

SwissProt: Q8C2K1 Mouse

Unigene: 15476 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
国产亚洲午夜精品a一区二区 | 亚洲国产18成人中文字幕久久久久无码av | 国产69精品久久久久APP下载 | 亚洲精品欧美精品中文字幕 | 国产精品欧美激情第一页 | 国产免费久久久久久久无码浪潮 | 校园久久综合激情四射伊人丁香 | 91精品国产福利资源在线观看麻豆 | 日韩国产自产拍av在线 | 高潮无码精品色欲av午夜福利 | 国产午夜视频在线观看720P | 国产欧美日韩精品视频一区二区三区 | 国产精品自在拍在线播放 | 国精品无码人妻一区二区三区 | 精品国产午夜福利在线观看 | 精品国产乱子久久久久 | 国产主播AV福利精品一区 | 伊人久久大香线蕉亚洲五月天 | 欧美一级特黄乱妇高清视频 | 我穿短裙被同桌cao得好爽 | 真人一级一级毛片免费观看 | 一二三四社区在线中文视频 | 久久久高清免费视频 | 中文国产高清综合乱色视频在线播放 | 亚洲精品高清一二区久久 | 好黄好猛好爽好痛的视频 | 老师好大好深好烫撑满了h 亚洲精品综合第一国产综合 | 午夜福利麻豆国产精品 | 久久aa毛片免费播放嗯啊 | 97精品一区二区视频在线观看 | 欧美日韩国产中文精品字幕自在自线 | 麻豆日产精品卡2卡3卡4卡5卡 | 日出水了特别黄的视频 | 小骚妇下面水多要插视频 | 亚洲精品宾馆在线精品酒店 | 有码中文无码中文无码人妻 | 宝贝别忍着喷出来嗯啊哦漫画 | 亚洲欧美日韩综合在线观看 | 69久久夜色精品国产69小说 | 欧美精品在线观看 | 国产AV无码国产AV毛片 |