亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产精品久久久久久无码人疌,国产精品成人一区二区无码欠欠源
Rabbit Anti-eNOS/BF594 Conjugated antibody (bs-20608R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-20608R-BF594
英文名稱 Rabbit Anti-eNOS/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的一氧化氮合成酶-3(內(nèi)皮型)抗體
別    名 NOS-3; cNOS; Constitutive NOS; EC NOS; ecNOS; Endothelial nitric oxidase synthase; Endothelial nitric oxide synthase; Endothelial nitric oxide synthase 3; Endothelial NOS; Nitric oxide synthase 3 (endothelial cell); Nitric oxide synthase 3; Nitric oxide synthase 3 endothelial cell; Nitric oxide synthase endothelial; nitric oxide synthase, endothelial; NOS 3; NOS III; NOS type III; NOS3; NOSIII; NOS3_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  內(nèi)皮細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Rat,  (predicted: Mouse, Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 133kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human eNOS/NOS-3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Nitric oxide synthase NOS oxidizes a guanidine nitrogen of arginine releasing nitric oxide in the form of a free radical and citrulline. Nitric oxide thus generated acts as a messenger in diverse functions including vasodilation neurotransmission, anti tumor and anti pathogenic activities. NOS is classified under three types: neuronal NOS (nNOS) or brain NOS (bNOS); inducible NOS (iNOS) or macrophage NOS (mNOS); and endothelial NOS (eNOS).
eNOS is a calcium/calmodulin dependent enzyme which undergoes several post translational modifications, including acylation with myristate and palmitate, and phosphorylation on numerous residues. As with the other members of the NOS family, eNOS derives the diffusible multifunctional second messenger NO from L arginine through a series of reactions in which L citrulline is an intermediate. eNOS plays an important role in controlling vascular tone, platelet aggregation, and cardiac myocyte function.

Function:
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.

Subunit:
Homodimer. Interacts with NOSIP and NOSTRIN.

Subcellular Location:
Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.

Tissue Specificity:
Platelets, placenta, liver and kidney.

Post-translational modifications:
Phosphorylation by AMPK at Ser-1177 in the presence of Ca(2+)-calmodulin (CaM) activates activity. In absence of Ca(2+)-calmodulin, AMPK also phosphorylates Thr-495, resulting in inhibition of activity. Phosphorylation of Ser-114 by CDK5 reduces activity.

Similarity:
Belongs to the NOS family.
Contains 1 FAD-binding FR-type domain.
Contains 1 flavodoxin-like domain.

Database links:

Entrez Gene: 287024 Cow

Entrez Gene: 4846 Human

Entrez Gene: 18127 Mouse

Entrez Gene: 24600 Rat

Omim: 163729 Human

SwissProt: P29473 Cow

SwissProt: P29474 Human

SwissProt: P70313 Mouse

SwissProt: Q62600 Rat

Unigene: 647092 Human

Unigene: 258415 Mouse

Unigene: 44265 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

合成與降解(Synthesis and Degradation)
催化生物體內(nèi)一氧化氮(NO)生成的酶。分神經(jīng)型一氧化氮合成的酶(nNOS or NOS-1)、誘導(dǎo)型一氧化氮合成的酶(iNOS or NOS-2)、內(nèi)皮型一氧化氮合成的酶(eNOS or NOS-3)。此抗體識別分子量為135kDa的內(nèi)皮型一氧化氮合成的酶。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
欧美97色伦欧美一区二区日韩 | 精品国产麻豆免费人成网站 | 一本大道香蕉高清久久 | 少妇性荡欲午夜性开放视频剧场 | av在线不卡网站无码18禁 | 在线视频这里只有精品 | 一级做a爰片久久毛片免费陪 | 久碰人澡人澡人澡人澡91 | 国产精品久久久天天影视香蕉 | 欧美va欧美va在线 | 夜夜爱成人免费网站 | 国产亚洲精品精品精品 | 国产精品嫩草影视在线观看 | 人妻熟妇久久久久久精品无码 | 强行挺进美艳老师的后臀 | 国产精品爱啪在线播放 | 国产SUV精品一区二区883 | 最近免费中文字幕MV免费高清版 | 亚洲无线一二三四区手机 | 成全视频高清免费观看在线动漫 | 亚洲1区2区3区精华液 | 国模丽丽啪啪一区二区 | 无码专区久久综合久综合字幕 | 亚洲国产欧美目韩成人综合 | 国产后进白嫩翘臀在线动漫 | 久久综合色天天久久综合图片 | 放荡女同老师和女同学生 | 把女人弄爽大黄A大片片 | 国产精品爱啪在线线免费观看 | 免费精品国产自产拍在线观看图片 | www.九色视频 | 欧美又大又粗又硬又色A片 国产精品久久久天天影视香蕉 | 日韩在线视频观看免费网站 | 中文字幕一区二区日韩欧美 | 91精品国产高清久久久久久 | 国产日产欧产精品精品浪潮 | 成人欧美一区二区三区白人 | 乌克兰粗大猛烈18P 最新国产毛2卡3卡4卡 | 女帝被扒开双腿疯狂输出 | 乖乖张开腿让我亲欲欲成欢 | 日本一卡二卡不卡视频查询 |