亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日韩亚洲人成在线,婷婷久久综合九色综合伊人色
Rabbit Anti-USP15/PE-Cy5.5 Conjugated antibody (bs-8752R-PE-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-8752R-PE-Cy5.5
英文名稱 Rabbit Anti-USP15/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標(biāo)記的去泛素化酶15抗體
別    名 Deubiquitinating enzyme 15; Deubiquitinating enzyme; EC 3 1 2 15; KIAA0529; MGC131982; MGC149838; MGC74854; Ubiquitin Carboxy terminal Hydrolase 15; Ubiquitin carboxyl-terminal hydrolase 15; Ubiquitin specific peptidase 15; Ubiquitin specific processing protease 15; Ubiquitin Specific Protease 15; Ubiquitin thioesterase 15; Ubiquitin thiolesterase 15; Ubiquitin-specific-processing protease 15; UBP 15; UBP15; UBP15_HUMAN; Unph 2; UNPH 4; Unph-2; Unph2; Unph4; USP 15.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  表觀遺傳學(xué)  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 112kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human USP15
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 Function:
Hydrolase that removes conjugated ubiquitin from target proteins and regulates various pathways such as the TGF-beta receptor signaling and NF-kappa-B pathways. Acts as a key regulator of TGF-beta receptor signaling pathway, but the precise mechanism is still unclear: according to a report, acts by promoting deubiquitination of monoubiquitinated R-SMADs (SMAD1, SMAD2 and/or SMAD3), thereby alleviating inhibition of R-SMADs and promoting activation of TGF-beta target genes (PubMed:21947082). According to another reports, regulates the TGF-beta receptor signaling pathway by mediating deubiquitination and stabilization of TGFBR1, leading to an enhanced TGF-beta signal (PubMed:22344298). Able to mediate deubiquitination of monoubiquitinated substrates as well as 'Lys-48'-linked polyubiquitin chains, protecting them against proteasomal degradation. May also regulate gene expression and/or DNA repair through the deubiquitination of histone H2B (PubMed:24526689). Acts as an associated component of COP9 signalosome complex (CSN) and regulates different pathways via this association: regulates NF-kappa-B by mediating deubiquitination of NFKBIA and deubiquitinates substrates bound to VCP. Protects APC and human papillomavirus type 16 protein E6 against degradation via the ubiquitin proteasome pathway.

Subunit:
A homodimer structure has been reported; however it is unclear whether the protein form a homodimer in vivo (PubMed:22001210). Identified in a complex with the COP9 signalosome complex (CSN). Interacts with SMAD1, SMAD2 and SMAD3; the interaction is direct. Forms a complex with SMURF2 and SMAD7. Interacts with TGFBR1. Interacts with SART3; the interaction is direct. May interact with RNF20 and RNF40. Interacts with human papillomavirus type 16 protein E6

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Expressed in skeletal muscle, kidney, heart, placenta, liver, thymus, lung, and ovary, with little or no expression in other tissues.

Post-translational modifications:
Phosphorylated. Phosphorylation protects against ubiquitination and subsequent degradation by the proteasome.
Ubiquitinated, leading to degradation by the proteasome.

Similarity:
Belongs to the peptidase C19 family.
Contains 1 DUSP domain.

Database links:

Entrez Gene: 395644 Chicken

Entrez Gene: 538284 Cow

Entrez Gene: 100055857 Horse

Entrez Gene: 9958 Human

Entrez Gene: 14479 Mouse

Entrez Gene: 100356438 Rabbit

Entrez Gene: 171329 Rat

Entrez Gene: 100542201 Turkey

Omim: 604731 Human

SwissProt: Q9Y4E8 Human

SwissProt: Q8R5H1 Mouse

Unigene: 434951 Human

Unigene: 244209 Mouse

Unigene: 470032 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
亚洲欧美国产精品专区久久综合高清 | 美国乱码日产精品BD在线观看 | 国产一级第一级毛片 | 她的丝袜脚胯下圣水尿 | 在线观看亚洲AV无码每日更新 | 亚洲日韩精品欧美一区二区一 | 91热久久免费精品99 | 亚洲国产另类久久久精品 | 国产亚洲日韩在线播放人成 | 国产精品TV在线麻豆 | 久久中文骚妇内射 | 日韩青草青草久热精品视频在线网站乱码 | 40岁成熟女人牲交片 | 午夜男女爽爽爽免费播放 | A国产一区二区免费入口 | 久久黄无码国内久久精品 | 麻花豆传媒剧在线观看免费高清 | 114一级毛片免费 | 激情欧美日韩一区二区 | 久久精品国产a真人一级无码毛片一区二区 | 粉嫩大学生无套内射无码专区久久 | 亚洲区中文字幕在线不卡电影 | 水蜜桃AV无码专区亚洲AV麻豆 | 为您提供久久久久精品免费看 | 精品一级 片内射视网站 | gvg454真实性教育在线播放 | 久久久久久精品天堂无码中文字幕 | 麻豆一区二区免费播放网站 | 啊灬啊灬啊灬快灬少妇 | 男人扎女下面很爽网站 | 国产精品毛片在线完整版的 | 国产欧美精品一区二区色综合 | 亚洲精品成a人在线观看 | 国产91无毒不卡在线观看 | 亚洲AV无一区二区三区 | 国产内射爽爽大片视频社区在线 | 日日躁夜夜躁狠狠久久AV | 美女又大又黄www免费网站 | 久久99久国产精品黄毛片 | 国产真人无遮挡作爱免费视频 | 一本久道综合在线无码人妻 |