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Rabbit Anti-Calcitonin/BF488 Conjugated antibody (bs-18210R-BF488)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-18210R-BF488
英文名稱 Rabbit Anti-Calcitonin/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的降鈣素抗體
別    名 Alpha CGRP; CALC 1; CALC A; CALC1; CALCA; Calcitonin related polypeptide alpha; CGRP 1; CGRP; CGRP I; CGRP-1; CGRPI; CGRP1; CT; Katacalcin; KC; MGC126648; alpha type CGRP; calcitonin 1; calcitonin gene related peptide 1; calcitonin gene related peptide I; calcitonin isoform CT preproprotein.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  神經(jīng)生物學(xué)  生長(zhǎng)因子和激素  內(nèi)分泌病  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Dog, Rabbit, Guinea Pig, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 3.5/13kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Calcitonin
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Calcitonin is a 32 amino acid peptide hormone synthesized by the parafollicular cells of the thyroid. It causes a rapid, but short lived, reduction in serum calcium and phosphate by promoting the incorporation of those ions in the bones. This effect is opposite to that of parathyroid hormone. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.

Function:
Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
Katacalcin is a potent plasma calcium-lowering peptide

Subcellular Location:
Secreted.

Similarity:
Belongs to the calcitonin family.

Database links:

Entrez Gene: 796 Human

Omim: 114130 Human

SwissProt: P01258 Human

Unigene: 37058 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

降鈣素(CT)是甲狀腺濾泡旁細(xì)胞(C細(xì)胞)分泌的含有32個(gè)氨基酸的單鏈多肽,可使血鈣、磷水平降低的一種多肽激素,腦組織和垂體含有降鈣素,前列腺等其他組織也存在CT。主要用于C細(xì)胞增生和甲狀腺髓樣癌的診斷、也可用于其他類型的神經(jīng)內(nèi)分泌腫瘤的研究。
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