亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
4455vw亚洲毛片,成全视频在线观看免费高清版,久久夜色撩人精品国产小说
Rabbit Anti-Neuropilin 1 /PE-Cy5 Conjugated antibody (bs-23865R-PE-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-23865R-PE-Cy5
英文名稱 Rabbit Anti-Neuropilin 1 /PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標(biāo)記的神經(jīng)纖毛蛋白1抗體
別    名 Neuropilin-1; NRP-1; Neuropilin1; Neuropilin 1; BDCA4; CD 304; CD304; DKFZp686A03134; DKFZp781F1414; NEL like protein 1; Nel related protein 1; Neuropilin1; Neuropilin 1; Neuropilin1 transmembrane receptor; NP1; NRP 1; NRP; NRP1; OTTHUMP00000020818; OTTHUMP00000020820; OTTHUMP00000020821; Vascular endothelial cell growth factor 165 receptor; VEGF165R; A5 protein; BLOOD DENDRITIC CELL ANTIGEN 4; NRP1_HUMAN.   
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 免疫學(xué)  神經(jīng)生物學(xué)  生長因子和激素  細胞膜受體  內(nèi)皮細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Mouse, Chicken, Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 100kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Neuropilin 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Function:
The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis.
The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.

Subunit:
Homodimer, and heterodimer with NRP2. Interacts with FER. Binds PLXNB1.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted.

Tissue Specificity:
The expression of isoforms 1 and 2 does not seem to overlap. Isoform 1 is expressed by the blood vessels of different tissues. In the developing embryo it is found predominantly in the nervous system. In adult tissues, it is highly expressed in heart and placenta; moderately in lung, liver, skeletal muscle, kidney and pancreas; and low in adult brain. Isoform 2 is found in liver hepatocytes, kidney distal and proximal tubules.

Similarity:
Belongs to the neuropilin family.
Contains 2 CUB domains.
Contains 2 F5/8 type C domains.
Contains 1 MAM domain.

Database links:
Entrez Gene: 8829 Human

Entrez Gene: 18186 Mouse

Entrez Gene: 246331 Rat

Omim: 602069 Human

SwissProt: O14786 Human

SwissProt: Q5T7F3 Human

SwissProt: P97333 Mouse

SwissProt: Q6PAR3 Mouse

SwissProt: Q9QWJ9 Rat

Unigene: 131704 Human

Unigene: 653996 Human

Unigene: 271745 Mouse

Unigene: 10815 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD304是一種神經(jīng)元受體,被認為表達于眾多的非造血細胞上,包括神經(jīng)元、內(nèi)皮細胞和腫瘤細胞。在體外單核細胞和造血前體細胞衍生的CD1a+樹突狀細胞是CD304(BDCA-4/Neuropilin-1)。
與CD303(BDCA-2)一樣,CD304(BDCA-4)抗原特異性地表達于人血液和骨髓中的漿樣樹突狀細胞。與CD303(BDCA-2)不同的是,CD304(BDCA-4)在培養(yǎng)的漿樣樹突狀細胞上表達上調(diào),同時在培養(yǎng)的髓系細胞能被誘導(dǎo)表達。在感染的扁桃體中,CD304(BDCA-4)不僅表達于漿樣樹突狀細胞,而且在其它細胞上也能檢測到,如初級濾泡B輔助性記憶T細胞。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
久久91精品国产91久久户 | 久久国产欧美日韩精品免费 | 日韩经典欧美一区二区三区 | 高跟丝袜人妖ts被虐调教 | 国产又爽又黄无码无遮挡在线观点 | 国产精品久久无码一区二. 精品国产髙清在线看国产毛片 | 丰满少妇被猛烈进入无码蜜桃 | 国产美女主播一级成人毛片 | 国产大片内射1区2区 | 99久久久精品综合网 | 欧美又大又硬又粗BBBBB | 国产成都一二三四区 | 午夜女生自慰喷水在线 | 最近的中文字幕在线MV视频 | 日韩人欧美?片内射久久 | 天堂中文在线最新版WWW | 日本XXXXX黄区免费看下载 | 中文天堂在线WWW最新版官网 | 夜鲁夜鲁很鲁在线视频视频 | 国产欧美日韩灭亚洲精品 | 久久精品综合网人人妻 | 成人免费毛片内射美女APP | 日本一二三区视频在线 | 初高中生洗澡福利网站 | 一级毛片正片免费视频手机看 | 色一伦一情一区二区三区 | 青青草原综合久久大伊人精品 | 欧美日产国产精品日产 | 精品亚洲AV无码喷奶水在线观看 | 国产欧美性成人精品午夜 | 91精品在线免费视频 | 国产日韩欧美一区二区综合区 | 精品乱码久久久久久中文字幕 | 亚洲欧美日韩在线观看 | 无码人妻丰满熟妇啪啪网不卡 | 日本老妇一级特黄aa大片 | 欧美综合自拍亚洲综合百度 | 国产精品一区二区熟女不卡 | 五月天丁香婷深爱综合 | 精品粉嫩国产48尤物在线播放 | 久久久久久久Aⅴ无码免费网站 |