亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
欧美另类69xxxxx,国产精品老师色诱在线
Rabbit Anti-Neuropilin 1 /BF647 Conjugated antibody (bs-23865R-BF647)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-23865R-BF647
英文名稱 Rabbit Anti-Neuropilin 1 /BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的神經(jīng)纖毛蛋白1抗體
別    名 Neuropilin-1; NRP-1; Neuropilin1; Neuropilin 1; BDCA4; CD 304; CD304; DKFZp686A03134; DKFZp781F1414; NEL like protein 1; Nel related protein 1; Neuropilin1; Neuropilin 1; Neuropilin1 transmembrane receptor; NP1; NRP 1; NRP; NRP1; OTTHUMP00000020818; OTTHUMP00000020820; OTTHUMP00000020821; Vascular endothelial cell growth factor 165 receptor; VEGF165R; A5 protein; BLOOD DENDRITIC CELL ANTIGEN 4; NRP1_HUMAN.   
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 免疫學(xué)  神經(jīng)生物學(xué)  生長(zhǎng)因子和激素  細(xì)胞膜受體  內(nèi)皮細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Mouse, Chicken, Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 100kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Neuropilin 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Function:
The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis.
The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.

Subunit:
Homodimer, and heterodimer with NRP2. Interacts with FER. Binds PLXNB1.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted.

Tissue Specificity:
The expression of isoforms 1 and 2 does not seem to overlap. Isoform 1 is expressed by the blood vessels of different tissues. In the developing embryo it is found predominantly in the nervous system. In adult tissues, it is highly expressed in heart and placenta; moderately in lung, liver, skeletal muscle, kidney and pancreas; and low in adult brain. Isoform 2 is found in liver hepatocytes, kidney distal and proximal tubules.

Similarity:
Belongs to the neuropilin family.
Contains 2 CUB domains.
Contains 2 F5/8 type C domains.
Contains 1 MAM domain.

Database links:
Entrez Gene: 8829 Human

Entrez Gene: 18186 Mouse

Entrez Gene: 246331 Rat

Omim: 602069 Human

SwissProt: O14786 Human

SwissProt: Q5T7F3 Human

SwissProt: P97333 Mouse

SwissProt: Q6PAR3 Mouse

SwissProt: Q9QWJ9 Rat

Unigene: 131704 Human

Unigene: 653996 Human

Unigene: 271745 Mouse

Unigene: 10815 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD304是一種神經(jīng)元受體,被認(rèn)為表達(dá)于眾多的非造血細(xì)胞上,包括神經(jīng)元、內(nèi)皮細(xì)胞和腫瘤細(xì)胞。在體外單核細(xì)胞和造血前體細(xì)胞衍生的CD1a+樹突狀細(xì)胞是CD304(BDCA-4/Neuropilin-1)。
與CD303(BDCA-2)一樣,CD304(BDCA-4)抗原特異性地表達(dá)于人血液和骨髓中的漿樣樹突狀細(xì)胞。與CD303(BDCA-2)不同的是,CD304(BDCA-4)在培養(yǎng)的漿樣樹突狀細(xì)胞上表達(dá)上調(diào),同時(shí)在培養(yǎng)的髓系細(xì)胞能被誘導(dǎo)表達(dá)。在感染的扁桃體中,CD304(BDCA-4)不僅表達(dá)于漿樣樹突狀細(xì)胞,而且在其它細(xì)胞上也能檢測(cè)到,如初級(jí)濾泡B輔助性記憶T細(xì)胞。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
亚洲国产成人AV网站 | 插我舔内射18免费视频 | 精品综合久久久久久88 | 免费一级肉体全黄毛片365看片 | 国产一区二区免费在线观看 | 爽到高潮无码视频在线观看 | 短篇公交车高H肉辣全集目录 | 亚洲欧美一区二区三区导航 | 国产不卡高清在线观看视频 | 黄色毛片视频免费 | 黄色视频在线观看网站 | 亚洲色欲色郤久久综合影院 | 人妻体内射精一区二区 | 扒开双腿猛进入爽爽在线观看 | 又黑又粗大棒插白妇口视频 | 日韩美女做暖暖免费视频 | 久久久97精品国产一区蜜桃 | 亚洲AⅤ日韩久久久久久 | 97精品伊人久久大香线蕉 | 人与ZO00 视频 | 国产成人精品AA毛片 | 按摩媚药无码中文字幕 | 中文字日产幕码三区的做法大全 | 91精品久久高清动漫 | 久色乳综合思思在线视频 | 男女性爽大片在线观看 | 久99久精品视频免费观看v | 韩国三级理论在线电影 | 美女裸体动态图片 | 色涩网站在线观看 | 黑人xxxx性hd极品 | www.xxxx黄色视频 | 久久综合色一综合色88 | 亚洲AV成人男人的天堂网 | 精品国产乱码久久久久久浪潮小说 | 亚洲中文字幕婷婷在线 | 亚洲v无码专区国产乱码一区二区 | 日韩亚洲人成网站在线播放 | 毛片免费高清免费 | 国产精品成人一区二区无码欠欠源 | 粗大的内捧猛烈进出在线视频 |