亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
怡红院日本一道日本久久,欧美精品一区二区三区久久久精品
Rabbit Anti-Neuropilin 1/Cy7 Conjugated antibody (bs-23866R-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-23866R-Cy7
英文名稱 Rabbit Anti-Neuropilin 1/Cy7 Conjugated antibody
中文名稱 Cy7標(biāo)記的 神經(jīng)纖毛蛋白1抗體
別    名 Neuropilin-1; NRP-1; Neuropilin1; Neuropilin 1; BDCA4; CD 304; CD304; DKFZp686A03134; DKFZp781F1414; NEL like protein 1; Nel related protein 1; Neuropilin1; Neuropilin 1; Neuropilin1 transmembrane receptor; NP1; NRP 1; NRP; NRP1; OTTHUMP00000020818; OTTHUMP00000020820; OTTHUMP00000020821; Vascular endothelial cell growth factor 165 receptor; VEGF165R; A5 protein; BLOOD DENDRITIC CELL ANTIGEN 4; NRP1_HUMAN.   
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 免疫學(xué)  神經(jīng)生物學(xué)  生長因子和激素  細(xì)胞膜受體  內(nèi)皮細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 100kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Neuropilin 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Function:
The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis.
The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.

Subunit:
Homodimer, and heterodimer with NRP2. Interacts with FER. Binds PLXNB1.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted.

Tissue Specificity:
The expression of isoforms 1 and 2 does not seem to overlap. Isoform 1 is expressed by the blood vessels of different tissues. In the developing embryo it is found predominantly in the nervous system. In adult tissues, it is highly expressed in heart and placenta; moderately in lung, liver, skeletal muscle, kidney and pancreas; and low in adult brain. Isoform 2 is found in liver hepatocytes, kidney distal and proximal tubules.

Similarity:
Belongs to the neuropilin family.
Contains 2 CUB domains.
Contains 2 F5/8 type C domains.
Contains 1 MAM domain.

Database links:
Entrez Gene: 8829 Human

Entrez Gene: 18186 Mouse

Entrez Gene: 246331 Rat

Omim: 602069 Human

SwissProt: O14786 Human

SwissProt: Q5T7F3 Human

SwissProt: P97333 Mouse

SwissProt: Q6PAR3 Mouse

SwissProt: Q9QWJ9 Rat

Unigene: 131704 Human

Unigene: 653996 Human

Unigene: 271745 Mouse

Unigene: 10815 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD304是一種神經(jīng)元受體,被認(rèn)為表達(dá)于眾多的非造血細(xì)胞上,包括神經(jīng)元、內(nèi)皮細(xì)胞和腫瘤細(xì)胞。在體外單核細(xì)胞和造血前體細(xì)胞衍生的CD1a+樹突狀細(xì)胞是CD304(BDCA-4/Neuropilin-1)。
與CD303(BDCA-2)一樣,CD304(BDCA-4)抗原特異性地表達(dá)于人血液和骨髓中的漿樣樹突狀細(xì)胞。與CD303(BDCA-2)不同的是,CD304(BDCA-4)在培養(yǎng)的漿樣樹突狀細(xì)胞上表達(dá)上調(diào),同時(shí)在培養(yǎng)的髓系細(xì)胞能被誘導(dǎo)表達(dá)。在感染的扁桃體中,CD304(BDCA-4)不僅表達(dá)于漿樣樹突狀細(xì)胞,而且在其它細(xì)胞上也能檢測到,如初級(jí)濾泡B輔助性記憶T細(xì)胞。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国精产品自线在拍在线看 | 欧美精品一级AAAA片 | 91福利国产在线观看网站 | 波多野结衣的AV一区二区三区 | 小货SAO边洗澡边CAO你动漫 | 成年免费视频黄网站在线观看 | 国产精品视频全国免费观看 | 国产黄A真人一级无码毛片一区二区三区 | 日韩一卡2卡3卡4卡新区亚洲 | 亚洲AV午夜福利无码精品一区 | 欧美白人极品性喷潮 | 久久久久久曰本av免费免费 | 欧美日韩国产码综合一区在线 | 精品无人乱码一区二区三区 | 蜜臀AV一区二区三区人妻在线 | 日本一级婬片A片免费播放曰i | 黑人巨大精品欧美一区二区 | 亚洲成人电影在线观看精品国产 | 国产美女一级视频 | 亚欧洲乱码视频一二三区 | 亚洲精品无码久久久久久久久 | 欧美人与拘牲交大全O人禾 天天躁日日躁狠狠躁日日躁黑人 | 无码国模国产在线观看 | 国产精品成人久久久久无码 | 成年在线网站免费观看无广告 | 人妖和人妖互交性XXXX视频 | 亚洲欧洲无卡二区视頻 | 男女无遮挡XX00动态图120秒 | 中文日产乱幕九区无线码 | 国产精品va在线观看h | 精品少妇AV无码免费久久洗澡 | 国产区免费在线观看 | 久久97久久精品免费观看黑人 | AV午夜午夜快憣免费观看 | 少妇被粗大猛烈进出免费视频 | 国产乱码精品一区二区三区中文 | 品产品久精国精产拍20 | 国产真人无码作爱免费看 | 欧美性爱视频免费观看 | 高清精品美女在线播放 | 日韩精品午夜视频一区二区三区 |