亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
丝袜美腿国产综合久久,日韩一级片内射中文视
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-Neuropilin 1/PE-Cy7 Conjugated antibody (bs-23866R-PE-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-23866R-PE-Cy7
英文名稱 Rabbit Anti-Neuropilin 1/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標記的 神經(jīng)纖毛蛋白1抗體
別    名 Neuropilin-1; NRP-1; Neuropilin1; Neuropilin 1; BDCA4; CD 304; CD304; DKFZp686A03134; DKFZp781F1414; NEL like protein 1; Nel related protein 1; Neuropilin1; Neuropilin 1; Neuropilin1 transmembrane receptor; NP1; NRP 1; NRP; NRP1; OTTHUMP00000020818; OTTHUMP00000020820; OTTHUMP00000020821; Vascular endothelial cell growth factor 165 receptor; VEGF165R; A5 protein; BLOOD DENDRITIC CELL ANTIGEN 4; NRP1_HUMAN.   
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 免疫學(xué)  神經(jīng)生物學(xué)  生長因子和激素  細胞膜受體  內(nèi)皮細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 100kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Neuropilin 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Function:
The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis.
The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.

Subunit:
Homodimer, and heterodimer with NRP2. Interacts with FER. Binds PLXNB1.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted.

Tissue Specificity:
The expression of isoforms 1 and 2 does not seem to overlap. Isoform 1 is expressed by the blood vessels of different tissues. In the developing embryo it is found predominantly in the nervous system. In adult tissues, it is highly expressed in heart and placenta; moderately in lung, liver, skeletal muscle, kidney and pancreas; and low in adult brain. Isoform 2 is found in liver hepatocytes, kidney distal and proximal tubules.

Similarity:
Belongs to the neuropilin family.
Contains 2 CUB domains.
Contains 2 F5/8 type C domains.
Contains 1 MAM domain.

Database links:
Entrez Gene: 8829 Human

Entrez Gene: 18186 Mouse

Entrez Gene: 246331 Rat

Omim: 602069 Human

SwissProt: O14786 Human

SwissProt: Q5T7F3 Human

SwissProt: P97333 Mouse

SwissProt: Q6PAR3 Mouse

SwissProt: Q9QWJ9 Rat

Unigene: 131704 Human

Unigene: 653996 Human

Unigene: 271745 Mouse

Unigene: 10815 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD304是一種神經(jīng)元受體,被認為表達于眾多的非造血細胞上,包括神經(jīng)元、內(nèi)皮細胞和腫瘤細胞。在體外單核細胞和造血前體細胞衍生的CD1a+樹突狀細胞是CD304(BDCA-4/Neuropilin-1)。
與CD303(BDCA-2)一樣,CD304(BDCA-4)抗原特異性地表達于人血液和骨髓中的漿樣樹突狀細胞。與CD303(BDCA-2)不同的是,CD304(BDCA-4)在培養(yǎng)的漿樣樹突狀細胞上表達上調(diào),同時在培養(yǎng)的髓系細胞能被誘導(dǎo)表達。在感染的扁桃體中,CD304(BDCA-4)不僅表達于漿樣樹突狀細胞,而且在其它細胞上也能檢測到,如初級濾泡B輔助性記憶T細胞。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
久久久久久人妻精品三区 | 成人黄网站 免费视频 | 果冻传媒剧国产MV在线看 | 国产在线视频欧美一区二区三区 | 91免费精品国偷自产在线不卡 | 十八岁免禁止免费播放 | 毛片女人十八以上观看 | 人妻熟妇久久久久久精品无码 | 无码一级a一片免费看 | 黄网站在线观看高清免费 | 国产女同一区二区三区五区 | 久久婷婷国产剧情内射白浆 | 老色皮永久免费网站 | 性色A码一区二区三区天美传媒 | 人妻性奴波多野结衣无码 | 连续高潮抽搐爽死喷水流白浆无码 | 一个人免费观看视频www | 24小时在线观看视频免费 | 色费女人18毛片A级毛片视频老少妇 | 亚洲熟女乱色一区二区三区 | 国产成人精品无缓存在线播放 | 国产精品亚洲成人久久免费看 | 色综合天天综合网天天狠天天 | 午夜精品久久久内射近拍高清 | 欧美日韩一区二区综合在线视频 | 欧美一级特黄AAAAAAAA片在线看 | 超碰国产精品人人做人人爱 | 亚洲日韩中文字幕A∨ | FREE性丰满白嫩白嫩的HD | 国产在线码观看超清无码视频 | 日本中文字幕有码在线视频 | 国产精品99久久久久久宅男小说 | 国产3级在线观看 | 国产精品成人久久久久无码 | 国产在线观看片免费人成视频 | 亚洲欧美日韩在线观看 | 91久久国产最好的精华液 | 人人揉人人捏人人爽五月天 | 2018国产精华国产精品 | 国产精品酒店性爱视频 | 免费视频国产在线观看 |