亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
亚洲无人区码一二三码区别图片 ,亚洲AV无码乱码在线观看性色
首頁 > 產品中心 > 標記一抗 > 產品信息
Mouse Anti-human CD45-FITC/Cy5 Conjugated antibody (bsm-30083M-FITC-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bsm-30083M-FITC-Cy5
英文名稱 Mouse Anti-human CD45-FITC/Cy5 Conjugated antibody
中文名稱 Cy5標記的FITC標記小鼠抗人CD45單克隆抗體
別    名 B220; CD 45; CD-45; cd45 antigen; ec3.1.3.48; CD45R; GP180; GP180; GP 180; L CA; LCA; L-CA; Leukocyte common antigen; LY5; Ly-5 glycoprotein; Protein tyrosine phosphatase receptor type C; Protein tyrosine phosphatase receptor type c polypeptide; protein tyrosine phosphatase, receptor type, C; Receptor-type tyrosine-protein phosphatase C; PTPRC; PTPRC_HUMAN; SCID due to PTPRC deficiency; T200; T200 glycoprotein; T200 leukocyte common antigen; Human homolog of severe combined immunodeficiency due to PTPRC deficiency.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  神經生物學  信號轉導  干細胞  細胞表面分子  糖蛋白  細胞類型標志物  自然殺傷細胞  淋巴細胞  t-淋巴細胞  b-淋巴細胞  
抗體來源 Mouse
克隆類型 Monoclonal
交叉反應 Human, 
產品應用 Flow-Cyt=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 143kDa
性    狀 Liquid
濃    度 1mg/ml
免 疫 原
亞    型 IgG
純化方法 affinity purified by Protein G
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 2008].

Function:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.

Subunit:
Binds GANAB and PRKCSH. Interacts with SKAP1. Interacts with DPP4; the interaction is enhanced in a interleukin-12-dependent manner in activated lymphocytes. Contains 2 tyrosine-protein phosphatase domains.

Subcellular Location:
Membrane; Single-pass type I membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts.

Post-translational modifications:
Heavily N- and O-glycosylated.

DISEASE:
Defects in PTPRC are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T(-)B(+)NK(+) SCID) [MIM:608971]. A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. Patients present in infancy recurrent, persistent infections by opportunistic organisms. The common characteristic of all types of SCID is absence of T-cell-mediated cellular immunity due to a defect in T-cell development.
Genetic variations in PTPRC are involved in multiple sclerosis susceptibility (MS) [MIM:126200]. MS is a neurodegenerative disorder characterized by the gradual accumulation of focal plaques of demyelination particularly in the periventricular areas of the brain. Peripheral nerves are not affected. Onset usually in third or fourth decade with intermittent progression over an extended period. The cause is still uncertain.

Similarity:
Belongs to the protein-tyrosine phosphatase family. Receptor class 1/6 subfamily.
Contains 2 fibronectin type-III domains.
Contains 2 tyrosine-protein phosphatase domains.

Database links:

Entrez Gene: 5788 Human

Omim: 151460 Human

SwissProt: P08575 Human

Unigene: 654514 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
国产精品久久久久久亚洲小说 | 色偷偷亚洲第一综合网 | 国产一级特黄妇女A片 | 性欧美video另类hd尤物 | 国产真实乱子伦精品视频 | 男人的天堂精品国产一区 | 欧美日韩一区二区综合在线视频 | 午夜欧美日韩精品久久久久久 | 对白脏话肉麻粗话视频 | 国产精品美女www爽爽爽视频 | 狠狠做深爱婷婷久久综合一区 | 精品自拍视频五区六区在线观看 | 456亚洲影院在线观看 | 原神乳液狂飙开襟网站MIMEI | 一区二区三区国模大胆 | 一女侍七夫巨H双修 | 午夜欧美日韩国产福利91不卡一区二区三区 | 日本不卡高字幕在线2019 | 91热久久免费频精品动漫99 | 亚洲欧美一区二区三区导航 | 天天做天天添天天谢 | 亚洲精品无码av中文字幕网站 | 91久久久久久亚洲精品蜜桃 | 小龙女玉足娇喘蕾丝湿润 | 天天躁日日躁狠狠躁AV麻豆 | 菠萝菠萝蜜影视在线观看小草免费 | 在线视频一区二区三区不卡 | 97人视频国产在线观看 | 内射人妻无码色AV麻豆 | 国产乱子伦真实精品视频 | 亚洲女精品一区二区三区 | 国产欧美日韩灭亚洲精品 | 2019精品国产品免费观看 | 图片区乱熟图片区小说 | 一本—道久久a久久精品蜜桃 | 欧美亚洲另类丝袜自拍动漫 | 无码中字出轨中文人妻中文中 | 欧美透明丰满内衣内裤 | 成年网站免费视频A在线双飞 | 欧美精品视频免费观看 | 国产精品 久久久精品APP |