亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
老师你夹得好紧好爽动态图,国产AV麻豆mag剧集,91国内揄拍国内精品对白不卡
Mouse Anti-EpCAM/HRP Conjugated antibody (bsm-51174M-HRP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bsm-51174M-HRP
英文名稱 Mouse Anti-EpCAM/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標(biāo)記的小鼠抗上皮細(xì)胞粘附分子單克隆抗體
別    名 Adenocarcinoma associated antigen; CD326; CD326 antigen; Cell surface glycoprotein Trop 1; CO17 1A; EGP; EGP40; Ep CAM; Epithelial cell surface antigen; Epithelial cellular adhesion molecule; Epithelial glycoprotein; GA733 2; hEGP 2; KS 1/4 antigen; KSA; Lymphocyte antigen 74; M1S2; M4S1; Major gastrointestinal tumor associated protein GA733 2; MIC18; MK 1; TACD1; TACSTD1; TROP1; Tumor associated calcium signal transducer 1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  細(xì)胞粘附分子  細(xì)胞表面分子  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 10A8
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用 WB=1:500-2000 ELISA=1:100-1000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EpCAM
亞    型 IgG1
純化方法 affinity purified by Protein G
儲 存 液 Constituents: 0.01M PBS, pH 7.4 with 10 mg/mL BSA and 0.1% Gentamicin, 50% glycerol. Or Lyophilized. Buffer = 0.01M PBS, pH 7.4 with 10 mg/mL BSA and 0.1% Gentamicin. Reconstitute with sterile distilled water.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]

Function:
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

Subunit:
Monomer. Interacts with phosphorylated CLDN7.

Subcellular Location:
Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Co-localizes with CLDN7 at the lateral cell membrane and tight junction.

Tissue Specificity:
Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma.

Post-translational modifications:
Hyperglycosylated in carcinoma tissue as compared with autologous normal epithelia. Glycosylation at Asn-198 is crucial for protein stability.

DISEASE:
Defects in EPCAM are the cause of diarrhea type 5 (DIAR5) [MIM:613217]. It is an intractable diarrhea of infancy characterized by villous atrophy and absence of inflammation, with intestinal epithelial cell dysplasia manifesting as focal epithelial tufts in the duodenum and jejunum. Defects in EPCAM are a cause of hereditary non-polyposis colorectal cancer type 8 (HNPCC8) [MIM:613244]. HNPCC is a disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early-onset colorectal carcinoma (CRC) and extra-colonic tumors of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the Western world. Clinically, HNPCC is often divided into two subgroups. Type I is characterized by hereditary predisposition to colorectal cancer, a young age of onset, and carcinoma observed in the proximal colon. Type II is characterized by increased risk for cancers in certain tissues such as the uterus, ovary, breast, stomach, small intestine, skin, and larynx in addition to the colon. Diagnosis of classical HNPCC is based on the Amsterdam criteria: 3 or more relatives affected by colorectal cancer, one a first degree relative of the other two; 2 or more generation affected; 1 or more colorectal cancers presenting before 50 years of age; exclusion of hereditary polyposis syndromes. The term 'suspected HNPCC' or 'incomplete HNPCC' can be used to describe families who do not or only partially fulfill the Amsterdam criteria, but in whom a genetic basis for colon cancer is strongly suspected. Note=HNPCC8 results from heterozygous deletion of 3-prime exons of EPCAM and intergenic regions directly upstream of MSH2, resulting in transcriptional read-through and epigenetic silencing of MSH2 in tissues expressing EPCAM.

Similarity:
Belongs to the EPCAM family.
Contains 1 thyroglobulin type-1 domain.

Database links:

Entrez Gene: 4072 Human

Entrez Gene: 17075 Mouse

Entrez Gene: 171577 Rat

Omim: 185535 Human

SwissProt: P16422 Human

SwissProt: Q99JW5 Mouse

SwissProt: O55159 Rat

Unigene: 542050 Human

Unigene: 4259 Mouse

Unigene: 106481 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
女人被狂躁C到高潮 | 色se01短视频永久免费 | 久久精品中文字幕无码有码 | 一级a性色生活片久久无 | 91亚洲精品福利在线播放 | 国产精品一区二区在线观看99 | 久久99久久99精品免视看国产四区 | 日本有码在线中文字幕 | 国产精品福利电影 | 国产成人精品免费久久久久 | 连续高潮抽搐爽死喷水流白浆无码 | 国产网址在线观看 | 亚洲一区二区黄色 | 欧美午夜精品一区二区蜜桃 | 黑巨人与欧美精品一区 | 亚洲天天在线日亚洲洲精 | 久久国产精品-久久精品 | 国产福利影院在线观看 | 亚洲日韩一区在线观看 | 久久精品国产欧美日韩99热 | 果冻传媒剧国产MV在线看 | 亚洲精品无码天堂AV | 日韩一区精品视频一区二区 | 黄色毛片视频免费 | 快插我BB好爽舔我视频 | 草草在线观看视频 | 中文字幕网伦射乱中文 | 伊人狠狠丁香婷婷综合尤物 | 性欧美18处19处破在线观看 | 91精品国产综合久久久久久 | 国产精品看片在线观看 | 国内精品人妻色欲无码久久久 | 特级毛片A级毛片免费观看网站 | 精品国产午夜福利精品推荐 | 香蕉国产片一级一级一级一级 | 公车痴汉媚药强抹在线观看 | 巨胸爆乳美女露双奶头挤奶 | 国产成人免费高清激情视频 | 亚洲日韩国产成在线发布一区二区三区 | 人妻精品久久无码专区人妻 | 毛片无码免费无码播放 |